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Patheon Inc.	Engineering of Pharmaceutical Materials: An Industrial Perspective Crystal engineering provides a rational approach to solving formulation, processing and product performance problems. This review discusses how the concept of crystal engineering can be judiciously utilized to manipulate the solid-state properties of drugs and excipients for successful pharmaceutical formulation and process development. Existing and emerging manufacturing as well as ...

APQC	New Product and Service Innovation: Improving Front-End Effectiveness As organizations better refine their product and service development processes, they increasingly turn their attention to what occurs at the front end. The old adage “garbage in, garbage out” is so true in product development. Getting better ideas and then taking them through an efficient and effective process can only improve the outputs and outcomes of the entire product or service development ...

United States Biological	United States Biological ELISA General Protocol The protocols described in this paper are for general application. Any product specific protocol supercedes these general recommendations: •Direct ELISA is suitable for the detection of protein-based antigens can be performed when the desired antibody is available in a conjugated form. •Indirect ELISA is required if the primary antibody is not conjugated. With Indirect ELISA, a conjugated ...

amsbio	Highly Reproducible Gene Delivery for Stem Cell Research AMSBIO have announced a range of ready-to- use lentivirus supernatant products suitable for many kinds of gene delivery applications including mammalian protein expression, stable cell line construction, cell signal pathway localization and stem cell research. Converting fully differentiated mouse or human somatic cells into embryonic-like cells (so called induced Pluripotent Stem Cell: iPSC) ...

Technology Business Research (TBR)	Business Intelligence Services Continue to Grow Despite Weak Economic Climate Throughout the economic downturn of 2008 and 2009, which dramatically impacted IT service spending, the Business Intelligence (BI) market remained a bright spot. In fact, many vendors experienced double-digit or even triple-digit growth of BI-related services in 2009, while experiencing revenue declines through the remainder of their portfolios. Challenging economic times have created the need ...

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Pharmaceuticals Research Library

Pace Analytical Life Sciences, LLC	Trace Level Moisture ANalysis in Biomaterials and Headspace

Parameter Generation & Control, Inc.	Issues to Consider When Complying With ICH Guidelines Involving Temperature and ... On the surface, providing a specified humidity and temperature for stability testing may appear easier to achieve than the 5% RH and 2C ICH guidelines would seem to indicate. The ability to control humidity at 2% does not mean that you are safely within the 5% RH tolerance dictated by ICH. The ability to produce a recording, display, or printout that is within a specified tolerance may not be a ...

Mar Cor Purification	Research Topic: Actril Cold Sterilant and Surface Challenge Test (USP <1072>) Actril Cold Sterilant is an US EPA registered disinfectant that has a broad range of disinfection claims. Actril Cold Steril- ant is used in a wide range of healthcare and clean room facilities. This technical white paper examines the use of Actril Cold Sterilant in a pharmaceutical manufacturing en- vironment that complies with USP-NF <1072>: Disinfectants and Antiseptics. Actril Cold Sterilant ...

EMD Chemicals Inc.	TGF-B Signalling: Dual Role in Tumor Suppression and Oncogenisis Transforming growth factor- (TGF-), a member of the TGF superfamily of proteins that includes activins, inhibins, and bone morphogenetic proteins (BMPs), regulates a wide array of cellular processes including cell differentiation, cellular senescence, immune response, wound healing, and apoptosis. TGF- signaling promotes growth and development during early embryogenesis. However, in mature ...

Thermo Scientific Cell Culture and Bioprocessing	Thermo Fisher Scientific’s NIR Commitment to Biopharma Process variability is a leading cause in biopharmaceutical batch failure and impacts the value and profitability of the industry. Thermo Fisher Scientific controls inherent variability through the use of the Thermo Scientific Antaris line of Fourier transform near-infrared (FT-NIR) spectrometers.

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BioClinica, Inc.	BioClinica Optimizer "How it Works" The competitive pressure to manage complexity and uncertainty in clinical trials has never been greater. To successfully forecast and manage clinical ...

Thermo Scientific Portal Optical Analyzers	Thermo Scientific TruScan The TruScan analyzer is the leading handheld Raman system for rapid, cost-effective material identity verification.

Thermo Scientific Cell Culture and Bioprocessing Pharmaceuticals

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