In “A Paradigm Shift in the Pharmaceutical Sales Model” Richard Johnston provided a historic perspective of the healthcare industry, the reasons for the industry's evolution and the recent shift from a provider-based selling model to an account-based sales strategy. We noted that, over the last twenty years, the pharmaceutical industry experienced extraordinary sales growth as a result of new ...
The science, art, and practice of protein purification have been with us for more than a century, yet, in many respects,
the field is only now evolving past its adolescent roots. New methods are replacing old methods at such a dizzying
pace, that even life-long experts in protein purification cannot keep up. In this article, we present many state-of-the-art
protein purification techniques ...
This article describes an investigation into why gelatin capsule
shells filled with hygroscopic materials sometimes crack. Its conclusions counter important aspects of the traditional theory.
As the popularity of liquid-filled hard capsules (LFHCs)
increases, formulators are becoming more interested in
ways to evaluate the compatibility of their formulations
with the capsule shell, ...
Over the past decade, seven best practices studies in the arena of HR development have documented the growing professionalism of corporate efforts in leadership development. In APQC's most recent study, we found fewer new concepts and tools but much more alignment and consistent use of the basics than we saw in previous projects. The distinctive quality of our best‐practice partners was more in ...
A crucial element in the development of topical and transdermal drug products is evaluation of the percutaneous absorption of the active pharmaceutical ingredient (API). Generally, the goal for topical products is to maximize cutaneous delivery of the API, whereas for transdermal products the goal is to achieve a specific rate of absorption sufficient to achieve a systemic blood level within the ...
Process variability is a leading cause in biopharmaceutical batch failure and impacts the value and profitability of the industry. Thermo Fisher Scientific controls inherent variability through the use of the Thermo Scientific Antaris line of Fourier transform near-infrared (FT-NIR) spectrometers.
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To show that Minncare is effective against other microorganisms, the following in vitro tests were performed using a .5% solution of Minncare. All tests were done on aqueous test solutions at 20°C.
On the surface, providing a specified humidity and temperature for stability testing may appear easier to achieve than the 5% RH and 2C ICH guidelines would seem to indicate. The ability to control humidity at 2% does not mean that you are safely within the 5% RH tolerance dictated by ICH.
The ability to produce a recording, display, or printout that is within a specified tolerance may not be a ...
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