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Radiochemicals
Research Library
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![Synthesis of Multi-Labeled [1,6-14C]-N-a-Fmoc-N-e-Boc-L-lysine](/css/buyerportal/images/icon_pdf_73x91.png "Synthesis of Multi-Labeled [1,6-14C]-N-a-Fmoc-N-e-Boc-L-lysine")
ABC Laboratories
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Lysine is an essential amino acid and a critical component of many peptides with an important biological role. Kumar and cowork- ers synthesized a series of lysine containing peptides (Ac-CIYKYY) by functional group modifications in the peptide side chain, to improve the inhibitory potency against Src kinase, which was suspected to cause the development of osteoporosis and in- flammation-mediated ...
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ABC Laboratories
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H2NOMe 1 Methyl 2-Methoxy-4-Amino-5-Chloro-Benzoate- [Carbonyl-14C] (MMACB-14C)1 is an important intermediate in the synthesis of several Carbon-14 labeled API's. Compound 1 was needed as an intermediate for a synthesis that required seven additional steps that resulted in an overall yield of 36%. A better route was requred to make the synthesis more efficient.
Previous synthesis1,2 of ...
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ABC Laboratories
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Triethylenetetraamines (TETA) are important precursors for many diagnostic and therapeutic pharmaceutical agents.
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ABC Laboratories
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Diethyl oxalate is an important molecule with various applications including: total synthesis,1 biochemistry,2 materials science,3 and combinatorics.4 While unlabeled diethyl oxalate is commercially available5 and its synthesis has been reported,6 few attempts have been made to synthesize isotopically labeled (i.e. 13C or 14C diethyl oxalate). Furthermore, the few reported syntheses of 13C and ...
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SGS Life Science Services - Clinical Research
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Too often insufficient predictivity of early clinical data leads to unnecessary expenses at later stages of development. Explore the benefits of considering new approaches to clinical drug development.
Why consider new approaches to clinical drug development?
In a standard clinical development program, the confidence level of making the best decision (go, no-go) prior to conducting a first- ...
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