Contract Manufacturing
Research Library
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EMD Chemicals Inc.
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Transforming growth factor- (TGF-), a member of the TGF superfamily of proteins that includes activins, inhibins, and bone morphogenetic proteins (BMPs), regulates a wide array of cellular processes including cell differentiation, cellular senescence, immune response, wound healing, and apoptosis. TGF- signaling promotes growth and development during early embryogenesis. However, in mature ...
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Hyaluron Contract Manufacturing
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The advent of bubble elimination in a prefilled syringe offers many advantages worth exploring prior to deciding how a product is to be packaged for clinical studies or commercial distribution. This technique further enhances the benefits of prefilled syringes. Prefilled syringes vs. vials have become the container of choice for parenteral drug delivery. The increase in their use is directly ...
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Meridian Life Science, Inc.
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A clinical grade recombinant human Parvovirus B19 (HPVB19) vaccine has been developed to treat transient aplastic crisis (TAC) in patients with sickle cell anemia. The vaccine consists of two viral proteins (VP1 and VP2) in separate baculovirus vectors that are co-infected at the correct MOIs into Spodoptera frugiperda (Sf9) cells and that, upon expression, self assemble into immunogenic ...
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Accugenix
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The identification of fungi, especially filamentous fungi, has historically been a very difficult task. Due to the amount of experience required to accurately identify filamentous fungi to the species level, it has become acceptable to either identify these organisms to the genus level, or in some cases, simply identify them as “molds.” Over the years, there have been numerous attempts to ...
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Patheon Inc.
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In an era characterized by the need to continuously evaluate and bolster R&D pipelines, the increasing complexity and overall cost to develop and approve drug products, the trend toward genericization, and mounting pressures to both decrease prices and maximize profitability, the pharmaceutical industry has sought competitive advantage in lower cost manufacturing jurisdictions.
The ...
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