Laboratory Management
Research Library
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EMD Chemicals Inc.
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In unstressed cells, p53 is latent and is maintained at low levels by targeted degradation mediated by MDM2. Through its binding to p53, MDM2 can shuttle p53 out of the nucleus into the cytoplasm for degradation. When normal mammalian cells are subjected to stress signals, such as hypoxia, radiation, and chemotherapeutic drugs, p53 is phosphorylated at multiple sites, including those involved in ...
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Woodley Equipment Company Ltd
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Point Of Care Testing in Clinical Trials – Page 1
Point of care (POC) testing is diagnostic testing performed promptly and conveniently in the vicinity of the patient, avoiding the often lengthy procedure of sending samples to be processed in a central laboratory. This gives rise to the alternative names of near‐patient and bedside testing. The requirement for POC testing is increasing, with the ...
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Labconco Corp.
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Prescription drug development continues to increase in importance. In 2006, U.S. biopharmaceutical companies invested $56.1 billion in research and development of which $44.9 billion was conducted in the U.S.1 In 2008 alone, the U.S. Food & Drug Administration approved 24 new drugs.2 Pharmaceutical, biotechnology, chemical and healthcare companies are involved in the effort to identify new ...
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Ahura Scientific
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The purpose of this paper is to discuss the application of Raman spectroscopy to the unique requirements of raw material testing. In order to do so we will answer the following questions: 1. What is and why perform identity testing? 2. What are the incentives to speed up testing? 3. Should we consider modifying the testing process? 4. How does the TruScan handheld Raman instrument perform ID ...
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Brookhaven Instruments Corporation
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