Revenue Management
Research Library
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Kinapse
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We believe that the main reason for the apparent fall in productivity with increasing scale is the concomitant increase in organizational complexity. It is our premise that breaking Big Pharma into entities of more manageable scale will assist them in increasing R&D productivity. Horizontal disintegration (where end-to-end processes in the value chain are kept together, but the scopes of these ...
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CLM Matrix
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This paper shows how two products, Microsoft® Office and Microsoft SharePoint®, contribute to the powerful architectural design of the Microsoft Business Productivity Infrastructure (BPI). The BPI stack approach suggests that only by thinking at a capability level (for example, “What do users want to do?‖), and then adding the right aspects of capability in each place (client, server, and ...
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Kinapse
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Internet usage of Indian General Practitioners
A rapid development has taken place in the use of the Internet by the medical fraternity in India over past few years. General Practitioners (GPs) form a vital part of medical fraternity in India. To evaluate the opinions and perceptions of Indian GPs on the use of Internet for professional purposes, a survey was conducted. The survey was ...
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EMD Chemicals Inc.
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In unstressed cells, p53 is latent and is maintained at low levels by targeted degradation mediated by MDM2. Through its binding to p53, MDM2 can shuttle p53 out of the nucleus into the cytoplasm for degradation. When normal mammalian cells are subjected to stress signals, such as hypoxia, radiation, and chemotherapeutic drugs, p53 is phosphorylated at multiple sites, including those involved in ...
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Kinapse
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The traditional drug development paradigm must change. We propose a fundamentally new approach which will create a win-win partnership between industry, academia, health authorities, health technology assessment (HTA)/health economic program (HEP) bodies and patients. We call this new approach “Real World Development” the underlying principle of which is to constantly assess the product in as ...
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