DAVOSPHARMA

DavosPharma is the leading provider of chemistry and pharmaceutical services, offering solutions to many of the problems faced by both emerging biotechs and established multinationals during drug development.

It provides custom chemistry (novel raw materials, GMP intermediates, regulatory starting materials & APIs) and custom dosage forms (parenterals and orals), with supporting development, analytics, stability and regulatory documentation. We have successfully leveraged thirty-seven years of custom manufacturing experience, forming global strategic alliances with well-vetted, cGMP custom manufacturers in the EU, North America and Asia. Our expertise enables us to match your particular need with the supplier best able to deliver your project. Davos shares your risk by billing for deliverables, not best efforts, providing an additional level of assurance and oversight between you and the supplier.

Our tech-ops team includes some of the industry's most qualified and talented chemists, pharmacists, engineers, analysts, project managers, and pharmaceutical marketing experts. From drug discovery to commercial production, we have the experience and know-how to manage the complex activities and tight time lines required for successful pharmaceutical development. Over the past thirty-seven years, DavosPharma has played a vital role in the launch of more than forty of our clients' NCEs.

Today, we continue to expand our services. DavosPharma is now able to provide discovery services, including medicinal chemistry and biology.

600 East Crescent Avenue
Upper Saddle River, New Jersey 07458
United States
201.995.0070
201.995.0071 (Fax)

G. Marzoni
201.995.0070

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DAVOSPHARMA Formulation Management Products

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Pharmacy: Preformulation & Formulation Development DavosPharma’s capabilities include GLP/GMP facilities that provide the full spectrum of formulation

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DAVOSPHARMA	DAVOSPHARMA Document Two pharmaceutical companies were developing similar HIV/AIDS drugs. Both syntheses used hazardous diazomethane early in the synthesis. While undesirable for the long term, rapid development timelines required commercial scale-up of the diazomethane route until novel, less hazardous chemistry was developed. DavosPharma and our manufacturing partner scaled the chemistry from 1 kg to 100 kg the ...

DAVOSPHARMA	DAVOSPHARMA Document Case Study #2: API Custom Synthesis and Formulation Development An emerging pharmaceutical company in- licensed an API that had only been made at the gram scale at the innovator company. As the emerging pharmaceutical company was completely virtual, with no synthetic chemistry or pharmaceutical development labs, they were completely reliant upon outsourcing to meet their demanding project ...

DAVOSPHARMA	DAVOSPHARMA Document Case Study #3: From Synthesis Procedures to Clinic in Five Months DavosPharma was requested to provide a preliminary quotation for manufacture of a novel API and tablet dosage form that included filing an IND for human clinical trials to support a client’s in-licensing efforts. The client provided well described experimental procedures for synthesis of the API and good preclinical ...

DAVOSPHARMA	DAVOSPHARMA Document Case Study #4: Innovation of Novel Synthetic Methods to Lower COG An intermediate manufactured by one of DavosPharma’ suppliers came under significant pricing pressure as part of an on-going program by the API innovator to lower the cost of goods (COG) of an AIDS drug. DavosPharma was instrumental in describing to the intermediate manufacturer’s management team the viability of the product. This ...

DAVOSPHARMA	DAVOSPHARMA Document Case Study #5: CMC Development Team for a Virtual Pharmaceutical Company An emerging pharmaceutical company had just in-licensed an active IND from a large pharmaceutical company. The virtual company had just raised their first tranche of funding and had no one on staff experienced with CMC development issues. DavosPharma was hired as overall project manager with the additional responsibilities ...

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