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Pharmaceuticals Research Library

Analysis of Human IgG using Automated Digestion Coupled Directly to the Triple Quad LCMS-8050
Shimadzu
Many pharmaceutical companies and research laboratories are interested in studying Immunoglobulin G (IgG) for its therapeutic and clinical advances. This note presents quantification of human IgG using an automated online trypsin digestion platform coupled directly to the LCMS-8050, a combination able to quantify IgG into the low fmol range, performing automated online digestion in less than 6 ...
 
Analysis of Antibody Aggregates Using the AXIMA MegaTOF High Mass MALDI-TOF Mass Spectrometer
Shimadzu
Antibody aggregation remains a complex question to address in the development and manufacture of therapeutic antibodies and biosimilars. This technical note illustrates the ability to characterize antibody aggregates by covalently stabilizing them with cross-linking reagents, fractionating the cross-linked aggregates by SEC and finally analyzing the fractions using the AXIMA MegaTOF.
 
Measurement of Elemental Impurities in Pharmaceutical Products by ICP-AES and ETAAS
Shimadzu
Widely used as trace metal analytical methods, ICP-AES and ETAAS are effective for analysis of metallic impurities in pharmaceutical products and their raw materials. This application presents such an analysis, with the commonly used anti-inflammatory analgesic acetylsalicylic acid (aspirin) as the sample.
 
New Data Processing Method for a Photodiode Array Detector
Shimadzu
Discover the Intelligent Dynamic Range Extension Calculator (i-DReC), which enables the automatic calculation of peak area and height. The i-DReC dramatically extends the linear dynamic range of calibration curves, enabling reliable quantitation of high concentration samples without need for sample dilution and reinjection.
 
Aroclors in Human Blood Serum by Triple Quadrupole GC/MS/MS
Shimadzu
GC methods for analysis of PCBs in biological samples range from simple screening by electron capture detector (ECD), to highly sophisticated isotope-dilution methods using magnetic sector mass spectrometry, with very little in between until now. This application describes a Multiple Reaction Monitoring (MRM) method for low-level detection of PCBs in human blood serum using the GCMS-TQ8030 triple ...
 

Pharmaceuticals Marketing Documents

High-Speed Liquid Chromatograph Mass Spectrometer
 
Cookie Cutter Proteolysis: Achieving Reproducible, Efficient Digestions for Proteomic Workflows
 
Mechanical Strength Evaluation of Functional Film Used in Smartphones
 
Determination of Drugs in Serum using Heart-cutting Two-dimensional Ultra High Performance Liquid Chromatography
 

Pharmaceuticals Video

Nexera UHPLC - Full Version Shimadzu Laboratory applications for LC systems are very diverse, extending from the product development phase to verification of quality. Therefore, a modular ...
 
Tracera - Plasma Technology is the Future of GC Dectection Shimadzu The new Tracera GC System is now ready to solve your trace analysis needs. This system utilizes the new Barrier Discharge Ionization Detector technology ...
 
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