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Polyclonal Antibodies

    
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Capralogics Inc.  Custom polyclonal antibody services, including host cell protein, single chain llama, goat antibodies, rabbit polyclonals, sheep antibodies, llama antibodies, camelid antibodies, bulk antibodies, chicken antibodies
 
5-Methyl Cytosine 5-Methyl Cytosine
 
5-Methyl Cytosine Sheep anti-5-methyl cytosine 250ug
 
United States Biological  USBiological is a long-established biotech manufacturer located near Boston, offering a wide range of biologicals, biochemicals and the largest selection of antibodies you will find anywhere. USBio offers over 650,000...
 
A0888-35F Triglycerides are the most efficient form of energy storage in mammalian adipose tissue during times of caloric excess. ATGL is one of the key enzymes...
 
A1059-62 Several common diseases such as type II diabetes, hypertension, cardiovascular diseases, hyperlipidemia, and some cancers are associated with obesity. An...
 
Clontech Laboratories  Clontech Laboratories provides kits, reagents, and services to help you explore questions about gene discovery, regulation, and function.
 
Dentin Matrix Protein-1 (DMP-1 or DMP1) Antibody Dentin matrix protein-1 is an acidic extracellular matrix phosphoprotein. DMP-1 is required for mineralization of bone and dentin, and is therefore...
 
Detection of His- & HA-Tagged Recombinant Proteins These antibodies detect his-tagged recombinant proteins in Western blot, ELISA, and immunocytohistochemical assays. They are highly sensitive and specific...
 
EMD Millipore Bioscience  The Bioscience portfolio delivers products & services for life science research in academic & pharmaceutical environments. Our focus on genomic, proteomic & cellular analysis is supported by sample preparation, research...
 
Anti- trimethyl Histone H3 (Lys9) Antibody Histones are highly conserved proteins that serve as the structural scaffold for the organization of nuclear DNA into chromatin. The four core histones,...
 
Anti-3-PGDH 3-PGDH (PHGDH) protein in an important enzyme in L-serine biosynthesis. 3-PGDH performs the first rate limiting step in the phosphorylated pathway of serine...
 
Randox Life Sciences  Randox Life Sciences is a recognised primary manufacturer of high quality and cost-effective human recombinant proteins, polyclonal and monoclonal antibodies providing custom antibody production.
 
17a-ESTRADIOL Boldenone is an anabolic steroid which is administered as boldenone undecylenate and is approved by the United States FDA for use in horses not intended for...
 
17a-NORTESTOSTERONE 17β, 19-nortestosterone, commonly known as nandrolone, is an anabolic androgen given by mouth and by injection. It is a natural hormone in some animal...
 
WuXi AppTec  Leading outsourcing company for pharmaceutical, biologics, and medical device with operations in China and the US; Biopharmaceutical, Pharmaceutical Discovery & Development, Toxicology, Bioanalytical, GMP Manufacturing,...
 
AIFM1 Antibody (N-term) Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
 
AMBRA1 Antibody (N-term) Purified Rabbit Polyclonal Antibody (Pab)
 
Rockland Immunochemicals, Inc.  Rockland is a manufacturer of antibodies, producer of blood products and cell cultures and custom antibody development partner.
 
Custom Monoclonal Antibody Production Rockland’s custom antibody production services allow you to direct the generation of your research required antibody. Let Rockland’s expertise aid you in...
 
GAPDH Antibody Anti-Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) (RABBIT) Antibody - 600-401-A33S
ProSci Incorporated  Antibody Supplier: Affinity-purified antibody, peptide-specific polyclonal antibodies to novel antigens, monoclonal antibody production, polyclonal antibody production, lysates, immunoblots, recombinant proteins
 
1110033M05RIK Antibody The amino acid sequence of 1110033M05Rik is derived from an annotated genomic sequence (NT_039589) using gene prediction method: GNOMON, supported by mRNA...
 
1110051B16RIK Antibody cDNA library was prepared and sequenced in Mouse Genome Encyclopedia Project of Genome Exploration Research Group in Riken Genomic Sciences Center and...
 
COVALAB  Custom antibody services : Development of Monoclonal and Polyclonal Antibodies-Peptide synthesis...Products :primary antibodies -Secondary Antibodies-Diagnostic kits - Functionalizated microtitration plates...
 
Anti-Chicken IgY, Peroxydase conjugate antibody Anti-Chicken IgY, Peroxydase conjugate antibody
 
Anti-Goat IgG (H+L), Alkaline phosphatase conjugate antibody Rabbit anti-goat IgG (H+L) F(ab')2 fragment
 
SDIX  antibody development, antibody production, monoclonal antibody, polyclonal antibodies, critical reagents, assay development, immunoassay development, antigen design, genomic antibody technology, GAT, genomic antibodies,...
 
Large Scale Production To provide maximum antibody yield during production, SDIX examines the viability of your cell line and the clonality of your cell line. Clonality is the...
 
Polyclonal Antibody Production We offer polyclonal antibodies from many different species which include Rabbit, Goat, Sheep, Chicken, Mouse, Guinea Pig, and Hamster. Polyclonal antibodies...
Maine Biotechnology Services  Maine Biotechnology Services provides custom monoclonal antibody development, polyclonal antibody development, matched pair analysis, bulk antibody production, antibody purification services, and assay development...
 
Antibody Production Services- Maine Biotechnology Services Maine Biotechnology Services offers both in vivo and in vitro antibody production in our cGMP facility at pilot and bulk scales. In Vivo Monoclonal...
 
Goat Polyclonal Antibody to Human IgE, affinity pure - PAB203P Goat Polyclonal Antibody to Human IgE, affinity pure Isotype: Goat Clone Number:
 
Denovo Biotechnology  Custom monoclonal antibodies, custom polyclonal antibodies from mouse, goat, sheep, chicken, donkey and llama. Protein expression, production scale-up, purification and characterization services, Molecular biology...
Affinity Biologicals Incorporated  Affinity Biologicals-manufacturer of factor deficient plasmas, coagulation proteins and enzymes, polyclonal antibodies, ELISA kits, Factor VIII, Factor IX, coagulation reagents, matched pair antibodies sets, proficiency...
 
a1-Antitrypsin, human a1-Antitrypsin, human
 
a2-Antiplasmin, human a2-Antiplasmin, human
 
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Polyclonal Antibodies - Product Reviews

Exciting new packaging materials for polyclonal antibodies: chicken eggs

A wide range of animals are used in the production of polyclonal antibodies. Although mammals are most commonly used, "These data suggest that chickens are an alternative model for producing pAbs (polyclonal antibodies) against mammal high-homology proteins such as MT (metallothioneins)" reports Angélica María Ortiz-Bueno, et al in Applied Biochemistry and Biotechnology, online issue 1559-0291.

Chicken hosts have several advantages, the most interesting of which is the fact that the antibodies are conveniently packaged in the chicken eggs, which can be stored for a long time. Other advantages include the fact that chickens produce 10 to 20 times more chicken egg yolk immunoglobulins (IgY) and are less expensive to maintain than rabbits and, while IgG made from a recombinant protein using a mammalian host takes 6 to 9 month to produce, IgYs only take 3 months. In addition, 300 million years separate chickens from the human evolutionary line in contrast to rabbits and mice with only 60 million years of separation. The result is that chickens generally mount a more vigorous immune response to most human gene products, including highly conserved ones.

Last but not least, the controversial subject of animal rights can be avoided by using chickens rather than mammals because, instead of having to be bled to yield the product, chickens deliver the polyclonal antibodies by simply doing what they do best: laying convenient, long-lasting sealed containers, in other words, eggs.


Best-in-Class Polyclonal Antibody Producers Who Use Chickens Feature:

  • Use of in-bred strains which have higher antibodies responses.
  • Immunization of birds before they begin to lay because stress of vaccination may adversely affect egg production.
  • Birds kept in housing conditions that encourage natural behavior and are protected from contamination.

Top Considerations Before Buying Polyclonal Antibodies Produced by Chickens:

Chicken IgY cannot be used in every situation so research should be done concerning whether IgY is appropriate for your particular line.


Key Producers:

1. Maine Biotechnology Services (MBS) offers complete antibody services, including hybridoma development, polyclonal antibody development, antibody production, purification and post processing. Its MultiPure technology enables customers to assess relative affinity, physical characteristics and matched pair capability before proceeding to subcloning. What sets it apart is its Academic Discovery Track, a scaled-down antibody development which is an affordable alternative for researchers and academics. MBS is continually expanding its product line and services. Recent additions include two antibodies that recognize large, small and branched versions of polyethylene glycol (PEG). This Portland, Maine-based company, founded in 1990, ships products to companies around the United States and in the European Union.

2. AMS Biotechnology (Europe) Ltd (amsbio) provides life science research reagents and services to small and medium-sized manufacturers. Its expanding catalogue contains 285,000 products. amsbio, which was founded in 1987 and restructured in 1997, specializes in Genomics, Proteomics and Immunology. This ISO 9001:2008 registered company offers custom polyclonal and monoclonal development services as well as thousands of protein specific polyclonal primary antibodies and isotype specific secondary antibodies conjugated with enzymatic and fluorescent indicators. Future plans include adding DNA damage screening, Cell Assays, Tumour Xenograft, and primate and rodent services. ambios is able to ship products to companies around the world from its offices in Switzerland, Germany and the UK.

3. United States Biological markets biochemicals, polyclonal antibodies, recombinant proteins, cell culture media and molecular biology kits to pharmaceutical and biotechnology companies in the United States and around the world. Customer service and technical support are available worldwide. US Biological markets 150,000+ products, but what sets it apart is its approach to customer helpdesk protocol. President Warren Shore says that, "We believe in answering all inquiries within a few hours of receipt. There is no voice mail at United States Biological...you always get to speak with humans..." Its headquarters are in Swampscott, Massachusetts.

4. Trevigen, Inc. is a privately-held biotechnology company that specializes in cancer research products, with an emphasis on apoptosis, DNA damage and repair and cancer cell function and behavior. This company was founded in 1992 and has a single office in Gaithersburg, Maryland. In 2008, it opened a new division, Trevigen Cell Assays, (TCA)  to offer contract research work to the pharmaceutical and biotechnology industries as well as government and academic research institutions, specializing in designing and conducting assays for lead compound and genotoxic screening based on DNA damage and repair and cancer cell behavior.

Polyclonal antibodies
Definition: Polyclonal antibodies (pAB) are a combination of immunoglobulin molecules that have been secreted in response to a specific antigen. The antigen is injected into an animal, inducing the B-lymphocytes to produce immunoglobulins specific for the antigen.

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Polyclonal Antibodies Research Library

A Guide to the Different Techniques in Which Antibodies are Used
Randox Life Sciences
A guide to the different techniques in which antibodies are used Enzyme Linked Immunosorbent Assay or ELISA is one of the most common tests conducted in immunobiochemistry. The principle involves immobilising antibodies onto a microtitre plate. These antibodies are labelled with an enzyme; the fixed enzyme reacts with the substrate to yield a coloured product allowing the qualification and ...
 
What are Polyclonal Antibodies?
Randox Life Sciences
A single immunoglobulin molecule is shown above, with the five main regions FAB, FC, Heavy chain, Light Chain and Complimentary Determining Regions (CDR). The FC region is mainly involved in compliment attachment via later stages of the immune response, which results in clearance of the antigen that the antibody has bound to. The FAB is mainly involved in scaffolding and orientating the CDR to ...
 
Putative prostate cancer (PCa) biomarker NAG detection is possible with H6D polymorphism  monoclonal and polyclonal antibodies f
Rockland Immunochemicals, Inc.
The nonsteroidal anti-­‐inflammatory drug-­‐activated gene (NAG1) also referred to as GDF-­‐15 or MIC-­‐1, is a member of the TGF-­‐β superfamily of cytokines. NAG1 is implicated in prostate cancer, and levels of NAG1 protein in the serum of patients with metastatic prostate carcinomas are significantly higher than those frompatients with breast and colorectal carcinomas. A correlation of the ...
 
Polyclonal Antibody Production
ProMab Biotechnologies, Inc
ProMab Biotechnologies, Inc. _____________________________ Phase I Immunization and anti-sera production ! Conjugated peptides or recombinant proteins are used to immunize two rabbits. ! Injections done every 2 weeks (4-6 injections) ! Pre-immune (5ml) and immune bleeds (100-120ml antiserum) are collected ! ELISA (and Western blot if protein antigen) to determine the titer ! Approximately 3 mg ...
 
Protein Purification - in Current Analytical Chemistry, 2009
Brighter Ideas, Inc.
The science, art, and practice of protein purification have been with us for more than a century, yet, in many respects, the field is only now evolving past its adolescent roots. New methods are replacing old methods at such a dizzying pace, that even life-long experts in protein purification cannot keep up. In this article, we present many state-of-the-art protein purification techniques ...
 

Polyclonal Antibodies Video

EMD Millipore Overview EMD Millipore Bioscience EMD Millipore is a leading supplier in the life sciences industry with over 60,000 products, tools and technologies on the market. We provide ...
 
AnaSpec's Speedy 28-Day Polyclonal Antibody Service - On the FastTrack Anaspec
 
Polyclonal Antibodies United States Biological Information

Polyclonal Antibodies News

Polyclonal Antibodies Rockland Immunochemicals, Inc. Pharmaceuticals
Polyclonal Antibodies EMD Millipore Bioscience Company
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