Product and Services Finder

RNA

    
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Clontech  Clontech Laboratories provides kits, reagents, and services to help you explore questions about gene discovery, regulation, and function.
 
Bovine Kidney Total RNA Total RNA, mRNA, available for bovine kidney and bovine lung. The highest quality RNA available at affordable pricing.
 
Bovine Liver Total RNA Total RNA, mRNA, available for bovine kidney and bovine lung. The highest quality RNA available at affordable pricing.
 
Fisher BioServices  The leader in critical biological material management with expertise in biobanking & biorepository, cell therapy solutions, clinical trial sample management, Bio-API management, and cold-chain logistics.
 
Biological Lab Processing Services FBS broad portfolio of leading life science tools and reagents include: specimen processing, blood separation and aliquoting. DNA/RNA and protein...
United States Biological  USBiological is a long-established biotech manufacturer located near Boston, offering a wide range of biologicals, biochemicals and the largest selection of antibodies you will find anywhere. USBio offers over 100,000...
 
Tissue, mRNA, Human Disease, liver cirrhosis, Diaphragm mRNA is isolated from total RNA obtained from human adult and fetal normal tissues, human tumor and diseased tissues, as well as from mouse, rat, monkey,...
 
Tissue, mRNA, Human Disease, liver cirrhosis, Kidney mRNA is isolated from total RNA obtained from human adult and fetal normal tissues, human tumor and diseased tissues, as well as from mouse, rat, monkey,...
 
Confluence Discovery Technologies, Inc.  Confluence is a Contract Research Organization providing Clients with 125+ Years of Drug R&D know-how and a proven track record having delivered 29 Phase I and 21 Phase II drug programs that resulted in 4 marketed...
 
Cell & Molecular Biology meeting drug target & biomarker requirements
 
Custom Assay Development when “OFF the SHELF” is not an option
RNA Health Information Systems  Pharmacy management software from RNA helps you attract and keep facility customers by improving the efficiencies and value-added services of your independent pharmacy. The Helix Pharmacy System equips you to fill orders...
Mirus Bio LLC  Mirus is the world leader in transfection reagents for chemical or electroporation delivery of DNA, RNA, siRNA, miRNA and other nucleic acids. Animal-free products are available for viral production, labeling chemistry is...
 
Label IT® Nucleic Acid Labeling Reagents Efficient, direct, non-enzymatic labeling of DNA and RNA
 
MIR 2150 A high efficiency, low toxicity, siRNA transfection reagent for mammalian cells 1ml
 
Silence Therapeutics  Silence Therapeutics is a leading UK biotechnology company that develops gene therapeutic technology based on RNA interference (RNAi). They focus on the developmental research of targeted RNAi and siRNA therapeutics for...
Jinfiniti Biosciences  Jinfiniti Biosciences provides genomics (DNA, RNA, microRNA extraction etc.) and proteomics services (biomarker discoveries etc.). Our high throughput technology is suitable for clinical trials, academic researches, CRO...
 
Total RNA Need total RNA for your experiments? Jinfinti Biosciences can provide high quality total RNA from whole blood or tissues. All our RNA has been isolated...
Enzymax LLC  Specialty proteins: AID, RNAP, Polymerase, Heat shock proteins Sumo proteinase, ULP1 Mini Spin Column for DNA and RNA Tini Spin column for DNA and RNA IP and CoIP columns G25 columns Spin filters
Cellecta, Inc.  Cellecta is a contract research service company that performs HT RNAi and peptide screens with pooled lentiviral bar-coded shRNA libraries.
 
Custom Pooled Lentiviral Bar-coded shRNA Libraries Cellecta has the expertise and capability to generate high quality pooled libraries consisting of virtually any defined sequences up to 200 bases in length....
 
Drug Target Discovery and Gene Function Analysis with RNAi Library Screening Using pooled lentiviral-based shRNA libraries, Cellecta has developed an effective, scalable, high-throughput platform for broad range screening and...
Reniguard Life Sciences, Inc.  Reniguard Life Sciences Inc is specialized in bioanalysis of macromolecules. We provide testing services, custom assays and assay kits for the detection of genes (DNA), gene transcripts (RNA), gene mutations, and gene...
Amsbio  AMS Biotechnology, Leader in developing modern products and technologies for life science research: Antibody, Protein, Peptide, Apoptosis, Migration, Cell Proliferation kits and reagents, Cytokines, Protein Kinases,...
 
39143 Pre-design Chimera RNAi i2 39143 Pre-design Chimera RNAi
 
39145 Pre-design Chimera RNAi i2 39145 Pre-design Chimera RNAi
 
Exiqon Life Sciences  Exiqon Life Sciences is a leading supplier of products for microRNA research. Researchers around the world in academia, the biotechnology industry and the pharmaceutical industry are using our research products to make...
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RNA - Product Reviews

Novel strategy for the treatment of heart failure: gene silencing via RNA gene transfer

A new approach to treating cardiac patients involves transferring RNA to the heart cells in order to influence gene expression. While the RNA function that usually comes to mind involves delivery of genetic information to ribosomes for protein manufacture, RNA also plays a role in regulating protein synthesis by influencing gene activity. Research is ongoing into employing RNA interference (RNAi) to silence specific genes, and microRNA (miRNA) modulations to change gene expression patterns. Once proven, the technologies behind target protein enhancement by gene transfer and target protein suppression by RNAi will enable research into the development of a new class of drugs.

Wolfgang Poller, et al. in the Oxford Journal reported that his team has solved the problem of vector targeting in their research into using cardiac-targeted RNAi strategy to control the regulator of cardiac contractility, phospholamban (PLB). Poller refers to RNA as “truly renaissance molecules" and says that "RNAi may provide an efficient, specific, and cheap solution to inhibit target genes.” He reports that “A major challenge for the future will be to identify the targets of miRNAs that participate in the respective pathomechanisms and to understand their mechanistic contribution in detail" but that "Under appropriate conditions, a therapeutic effect may be achieved not only in genetically determined but also in acquired diseases."


Best-in-Class RNA Products Providers:

  • Use disposable plasticware that has been certified to be RNAse-free and reagents prepared from RNAse-free components
  • Have a designated set of pipettes with sterile RNAse-free filter pipette tips for RNA work to prevent cross-contamination
  • Keep work surfaces and equipment clean with RNAse/DNAse decontamination solution


Top Considerations Before Selecting RNA Products Providers:

Frost-free units should not be used to store RNA samples. For short-term storage, -20 degrees Celsius is appropriate but for long-term, the temperature should be -80 degrees Celsius. Samples should not go through more than 5 freeze-thaw cycles.


Key Producers:

1. AMS Biotechnology (Europe) Ltd’s (amsbio) 285,000 product catalogue includes RNA extraction, amplification, analysis and RNA interference kits, in addition to thousands of reference universal and tissue specific total RNA and mRNA from a variety of species and tissues, Northern blots, matched total RNA, and unique matched DNA, RNA, proteins sets. GeneSilencer, a transfection reagent, enables transfection of siRNA into a variety of mammalian cells. According to ambio, its “Dicer siRNA Generation Kit allows easy and cost-effective generation of a large number of small interfering RNAs (siRNAs) from full-length target genes.” amsbio, which was founded in 1987, specializes in Genomics, Proteomics and Immunology. This ISO 9001:2008 registered company ships products to the global market from its offices in Switzerland, Germany and the UK.

2. High Throughput Genomics, Inc.’s (HTG) qNPA miRNA Microarrays, used to formulate smaller miRNA signatures for routine testing on the ArrayPlate, also enable miRNA sequences in human, rat, and mouse to be studied in the same microplate. HTG originally developed NPA™ technology to improve the drug discovery process. This technology is now being used for gene expression profiling, Translational Medicine and Diagnostic applications and the measurement of miRNA. HTG was established in 1997as a wholly owned subsidiary of SIDDCO and was spun-off in 2001. It is headquartered in Tucson AZ with a sales office in Madison, WI and distributors in Japan, Italy and the UK.

3. Bio-Synthesis Inc. offers integrated solutions for DNA microarray services and custom DNA-based diagnostic kits and consumables; custom RNA, DNA and peptide synthesis; DNA Real-Time PCR products; custom polyclonal antibody production; and molecular diagnostic detection kits. Services cover genomic, proteomic and cell biology. BSI reports that it was “the first producer of commercially available synthetic DNA” and that its "integrated manufacturing programs enable a seamless transition from the inception of an idea through product launch." This private company, located in Lewisville TX, was founded in 1984.

4. Affymetrix offers a GeneChip probe array for monitoring transcriptional regulation and antimicrobial agent response of P. aeruginosa and a GeneChip array. Its Made-to-Order Program offers both custom array designs and previous-generation GeneChip arrays no longer available in the catalog. Affymetrix began marketing the first commercial DNA microarray in the late 1980s. Today, Affymetrix reports that it "is evolving into a provider of scalable, innovative genomic analysis tools and reagents for discovery, exploration, validation, and genetic testing." This Santa Clara CA-headquartered company has offices in Ohio, the UK, Japan, Singapore and Shanghai China.

RNA
Definition: Ribonucleic acid (RNA) is a usually a single long polymer made up of nucleotides whose function is central to the synthesis of proteins. It is the genome of most viruses.

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RNA Research Library

Controlled-Rate Freezing of Cells During Ultra Cold Transit
Fisher BioServices
Patient cells that are isolated for development into a therapeutic product must be processed quickly or they lose their integrity and therapeutic value. Cells that cannot be processed immediately must be cryopreserved at -195°C in liquid nitrogen. However, to ensure viability and integrity upon thawing, freezing down to -195°C must be performed at a specific cooling rate, which requires ...
 
Role of Enzyme:Inhibitor Kinetic Characterization in Predicting Pharmacodynamic Response of Irreversible Fatty Acid
Confluence Discovery Technologies, Inc.
CASE STUDY: Role of Enzyme:Inhibitor Kinetic Characterization in Predicting DISCOVERY TECHNOLOGIES Pharmacodynamic Response of Irreversible Fatty Acid Amide Hydrolase (FAAH) Inhibitors Synopsis G G Src G/13 To investigatGeTtPhe reGlev-aOnce of in vitro inhibitor kiGneticsGto in vivo pharmacodynamicsS(PODS), a simple Pax PYK2 fluorogenic assay was used to determine the kinetic constants of ...
 
RNA quantitation with RNA and DNA extraction App note
ZyGEM
Sample normalisation with RNAGEM™ Tissue Michelle Miles and David Saul. ZyGEM Corporation Ltd, Waikato Innovation Park, Ruakura Road, Hamilton, New Zealand Introduction When working with low cell counts or cell lysates, most rapid methods designed for estimating total RNA quantity (such as optical density or fluorescent dyes) are insufficiently sensitive or affected by material in unpurified ...
 
Structure of HCV Polymerase in Complex with Primer - Template RNA
Emerald Bio
Structure of HCV Polymerase in Complex with Primer- Template RNA Mosley RT, Edwards TE, Murakami E, Lam AM, Grice RL, Du J, Sofia MJ, Furman PA, Otto MJ. Replication of the hepatitis C viral genome is accomplished by the NS5B RNA-dependent RNA polymerase (RdRp), for which mechanistic understanding and structure-guided drug design efforts have been hampered by its propensity to crystallize in a ...
 
Poster: Protein Levels and mRNA Knockdown: The importance of accurate protein quantification in RNA silencing using PCR, Western
LI-COR Biosciences
High quality quantitative analysis of RNA silencing was obtained using two applications of the Odyssey® Infrared Imaging system; the quantitative western blot and the In-Cell Western™ (ICW) assay. Cells transfected with Akt1 siRNA or scrambled siRNA (NS1) were subjected to both quantitative real time PCR (qRT-PCR) and quantitative Western blot analysis. Following Akt1 siRNA transfection, the Akt1 ...
 

RNA Video

SAFC Proligo TC RNA Phosphoramidites SAFC This video provide a step by step demonstration of SAFC offers a more time-sensitive and efficient solution to creating RNAs.
 
Direct-zol RNA MiniPrep Product Video Zymo Research
 
RNA United States Biological Company

RNA News

RNA Confluence Discovery Technologies, Inc. Information
RNA EMD Millipore Bioscience Company
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