Concentric Medical, Inc Concentric Medical, Inc., headquartered in Mountain View, CA, is a medical device company focused on the design, development and commercialization of products for restoring blood flow in patients who are experiencing an...
Emisphere Technologies Emisphere is a biopharmaceutical company that focuses on a unique and improved delivery of therapeutic molecules or nutritional supplements using its Eligen(R) Technology. These molecules and compounds could be currently...
AAIPharma Services Corp. Our services include: clinical packaging/distribution, solid dose & sterile contract manufacturing, analytical services, formulation development for solids and liquids, validation services, regulatory affairs and oral...
Oral Drug Delivery Systems
AAIPharma Services Formulation Development group has improved the pharmacokinetics of several drugs by developing technologies, processes, expertise, and...
ColorCon Colorcon is a world leader in the development, supply and technical support of formulated coatings and other excipients for the pharmaceutical industry. Our best-in-class products and pharmaceutical technologies are...
ETHOCEL™ Premium Ethylcellulose Polymers
Colorcon® strives to meet the needs of customers no matter what their formulation needs, and products like ETHOCEL™ enable Colorcon to do so because it has...
METHOCEL™ Cellulose Ethers (Controlled Release)
METHOCEL™ Premium grades have long been used by the pharmaceutical industry. There are two basic premium types, methylcellulose (MC) and hypromellose, which...
Aveva Drug Delivery Systems, Inc. Aveva Drug Delivery Systems is a Nitto Denko company that is solely dedicated to the development and advancement of transdermal drug delivery systems for select industry partners. Aveva is supported by Nitto Denko, a...
Cyclooxygenases (COXs), also known as prostaglandin H synthases, are fatty acid oxygenases that contain about 600 amino acid residues and act on arachidonic acid to generate prostaglandins (PG). All vertebrates contain two COX genes: one encoding the constitutive COX-1 and another inducible COX-2. COX-1 and COX-2 share approximately 60-65% amino acid identity. These COX isoforms are bifunctional ...
In unstressed cells, p53 is latent and is maintained at low levels by targeted degradation mediated by MDM2. Through its binding to p53, MDM2 can shuttle p53 out of the nucleus into the cytoplasm for degradation. When normal mammalian cells are subjected to stress signals, such as hypoxia, radiation, and chemotherapeutic drugs, p53 is phosphorylated at multiple sites, including those involved in ...
Transforming growth factor- (TGF-), a member of the TGF superfamily of proteins that includes activins, inhibins, and bone morphogenetic proteins (BMPs), regulates a wide array of cellular processes including cell differentiation, cellular senescence, immune response, wound healing, and apoptosis. TGF- signaling promotes growth and development during early embryogenesis. However, in mature ...
Telomerase is a specialized ribonucleoprotein composed of telomerase reverse transcriptase (TERT), an intrinsic RNA template (TR), and several associated proteins. Its main function is to stabilize telomeres, which protect chromosomes from recombination and end-to-end fusion.
Telomeres also recognize DNA damage and control the replicative capability of cells. With each cell division some of ...
Immunohistochemistry is widely used in basic research to understand the distribution and localization of biomarkers and differentially expressed proteins in different parts of a biological tissue. IHC staining is also widely used in the diagnosis of abnormal cells such as those found in cancerous tumors. Visualizing an antibody-antigen interaction can be accomplished in a number of ways. In the ...
Carestream is pleased to announce the release of our newest accessory for our advanced MI Software. With this powerful new addition, you can now perform ...
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