Bilcare Bilcare Research is an innovation-led solutions provider that partners with the global pharmaceutical and healthcare industry to improve patient healthcare outcomes. We endeavour to deliver effective and affordable...
Bilcare Global Clinical Supplies
Bilcare Global Clinical Supplies ("Bilcare GCS") serves the global pharmaceutical and bio-pharmaceutical industries with clinical trial materials support,...
Hercules Inc./ Aqualon Div. Aqualon has been delivering pharmaceutical performance since the 1950s. To find out more about Aqualon's products for pharmaceuticals, typical applications, our technical support resources, and contact for sales and other...
Zyleris Pharmatech Zyleris is specialized in developing innovative high-throughput experimentation technologies for topical and transdermal formulation development.
High throughput screening services
Preformulation and formulation development services for topical, transdermal and personal care products.
Catalent Pharma Solutions, Inc. Catalent offers a full range of product development services such as pre-clinical support, API development, analytical services, drug delivery development, clinical manufacturing, packaging, and regulatory consulting...
In an era characterized by the need to continuously evaluate and bolster R&D pipelines, the increasing complexity and overall cost to develop and approve drug products, the trend toward genericization, and mounting pressures to both decrease prices and maximize profitability, the pharmaceutical industry has sought competitive advantage in lower cost manufacturing jurisdictions.
The ...
In unstressed cells, p53 is latent and is maintained at low levels by targeted degradation mediated by MDM2. Through its binding to p53, MDM2 can shuttle p53 out of the nucleus into the cytoplasm for degradation. When normal mammalian cells are subjected to stress signals, such as hypoxia, radiation, and chemotherapeutic drugs, p53 is phosphorylated at multiple sites, including those involved in ...
Telomerase is a specialized ribonucleoprotein composed of telomerase reverse transcriptase (TERT), an intrinsic RNA template (TR), and several associated proteins. Its main function is to stabilize telomeres, which protect chromosomes from recombination and end-to-end fusion.
Telomeres also recognize DNA damage and control the replicative capability of cells. With each cell division some of ...
Cyclooxygenases (COXs), also known as prostaglandin H synthases, are fatty acid oxygenases that contain about 600 amino acid residues and act on arachidonic acid to generate prostaglandins (PG). All vertebrates contain two COX genes: one encoding the constitutive COX-1 and another inducible COX-2. COX-1 and COX-2 share approximately 60-65% amino acid identity. These COX isoforms are bifunctional ...
Transforming growth factor- (TGF-), a member of the TGF superfamily of proteins that includes activins, inhibins, and bone morphogenetic proteins (BMPs), regulates a wide array of cellular processes including cell differentiation, cellular senescence, immune response, wound healing, and apoptosis. TGF- signaling promotes growth and development during early embryogenesis. However, in mature ...
Affordable semi-automated (Click’n’Count) and automated (SuperCount), the aCOLyte colony counting systems greatly improve efficiency, reliability and ...
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