GEA Pharma Systems Supplies of advanced processing equipment for the manufacturing of oral and parenteral dosage forms - Granulation and Drying, Materials Handling, Tablet Compression and Lyophilization.
AccuChart The products available from AccuChart include 4 types of solid unit dope/bar code packaging systems- the Cadet, the Cadet Twin, The Cadet Twin 2x2, and the Punch Cadet- all for tablet and capsule unit does/bar code...
Velesco Pharmaceutical Services The founders of Velesco Pharmaceutical Services recognized the opportunity to capitalize on their research experience and expertise in early stage drug development gained during their tenure in the pharmaceutical...
GMP Clinical Trial Materials
Powder in bottle
Powder in capsule
Simple blends in capsule
Non-sterile liquids and semi-solids
Overencapsulation
Hand filled...
Honeywell Honeywell Process Solutions" goal is to improve customers" business performance by offering solutions that drive safety, quality, reliability, and efficiency. Honeywell can help customers reduce risk and costs, and...
Honeywell Dosage Form Manufacturing
In today's business environment, competition among commercial pharmaceutical manufacturers is becoming more intense. Companies are faced with price erosion...
CDI-Life Sciences
CDI-Life Sciences provides a full range of engineering, design, construction management, commissioning, validation, outsourcing and staffing solutions to pharmaceutical and biotechnology clients worldwide. CDI-Life...
In an era characterized by the need to continuously evaluate and bolster R&D pipelines, the increasing complexity and overall cost to develop and approve drug products, the trend toward genericization, and mounting pressures to both decrease prices and maximize profitability, the pharmaceutical industry has sought competitive advantage in lower cost manufacturing jurisdictions.
The ...
In unstressed cells, p53 is latent and is maintained at low levels by targeted degradation mediated by MDM2. Through its binding to p53, MDM2 can shuttle p53 out of the nucleus into the cytoplasm for degradation. When normal mammalian cells are subjected to stress signals, such as hypoxia, radiation, and chemotherapeutic drugs, p53 is phosphorylated at multiple sites, including those involved in ...
Transforming growth factor- (TGF-), a member of the TGF superfamily of proteins that includes activins, inhibins, and bone morphogenetic proteins (BMPs), regulates a wide array of cellular processes including cell differentiation, cellular senescence, immune response, wound healing, and apoptosis. TGF- signaling promotes growth and development during early embryogenesis. However, in mature ...
Telomerase is a specialized ribonucleoprotein composed of telomerase reverse transcriptase (TERT), an intrinsic RNA template (TR), and several associated proteins. Its main function is to stabilize telomeres, which protect chromosomes from recombination and end-to-end fusion.
Telomeres also recognize DNA damage and control the replicative capability of cells. With each cell division some of ...
Cyclooxygenases (COXs), also known as prostaglandin H synthases, are fatty acid oxygenases that contain about 600 amino acid residues and act on arachidonic acid to generate prostaglandins (PG). All vertebrates contain two COX genes: one encoding the constitutive COX-1 and another inducible COX-2. COX-1 and COX-2 share approximately 60-65% amino acid identity. These COX isoforms are bifunctional ...
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