NuSil Technology As a leading formulator and manufacturer of silicone compounds for healthcare, aerospace, electronics and photonics applications, count on NuSil to develop and deliver standard and customized silicone compounds designed...
Cirrus Pharmaceuticals, Inc. Cirrus Pharmaceuticals, Inc. is a contract product development company assisting biotechnology and pharmaceutical companies with dosage form development projects. Cirrus works with start-up, mid-size and multinational...
Zyleris Pharmatech Zyleris is specialized in developing innovative high-throughput experimentation technologies for topical and transdermal formulation development.
High throughput screening services
Preformulation and formulation development services for topical, transdermal and personal care products.
Cyclooxygenases (COXs), also known as prostaglandin H synthases, are fatty acid oxygenases that contain about 600 amino acid residues and act on arachidonic acid to generate prostaglandins (PG). All vertebrates contain two COX genes: one encoding the constitutive COX-1 and another inducible COX-2. COX-1 and COX-2 share approximately 60-65% amino acid identity. These COX isoforms are bifunctional ...
Telomerase is a specialized ribonucleoprotein composed of telomerase reverse transcriptase (TERT), an intrinsic RNA template (TR), and several associated proteins. Its main function is to stabilize telomeres, which protect chromosomes from recombination and end-to-end fusion.
Telomeres also recognize DNA damage and control the replicative capability of cells. With each cell division some of ...
In unstressed cells, p53 is latent and is maintained at low levels by targeted degradation mediated by MDM2. Through its binding to p53, MDM2 can shuttle p53 out of the nucleus into the cytoplasm for degradation. When normal mammalian cells are subjected to stress signals, such as hypoxia, radiation, and chemotherapeutic drugs, p53 is phosphorylated at multiple sites, including those involved in ...
Transforming growth factor- (TGF-), a member of the TGF superfamily of proteins that includes activins, inhibins, and bone morphogenetic proteins (BMPs), regulates a wide array of cellular processes including cell differentiation, cellular senescence, immune response, wound healing, and apoptosis. TGF- signaling promotes growth and development during early embryogenesis. However, in mature ...
Global clinical trial solutions. Real-world results.
The Case for Functional Outsourcing of EDC
The Business Case for Functional Outsourcing of EDC
Summary: This white paper is intended for clinical operations managers who are either considering their electronic data capture (EDC) options for the first time or re-evaluating previous decisions. This paper looks at the primary approaches for ...
The MICROLAB® NIMBUS is Hamilton Company's newest automated multi-channel pipetting platform, offering a high density deck layout in a body small enough ...
Viscira is dedicated to the development of new media communication solutions and interactive software applications for the life sciences industry. The ...
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