Product and Services Finder
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The Jackson Laboratory We discover precise genomic solutions for disease and empower the global biomedical community in our shared quest to improve human health. We offer an array of scientific products and services to meet your research needs.
Jackson Laboratory Services
We are an independent, nonprofit organization focusing on mammalian genetics research to advance human health. Our mission is to discover the genetic basis...
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Translational Drug Development (TD2) Translational Drug Development (TD2) is a biopharma service provider uniquely positioned to meet your development challenges. TD2 integrates world-class clinical and regulatory expertise with "-omic" science and provides...
Preclinical Services
TD2 provides strong support for the clinical development program by offering innovative preclinical services. TD2 designs and executes in vitro and in vivo...
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Myriad RBM, Inc. Myriad RBM is a CLIA-certified biomarker testing laboratory specializing in cost-effective, high-quality multiplexing services. Our protein immunoassays benefit drug discovery & development from preclinical through Phase...
RodentMAP® v2.0
A 58-biomarker Multi-Analyte Profile (MAP) focused on the identification of biomarker patterns in rodent biological samples, such as serum or plasma. Myriad...
Services Provided
Myriad RBM, Inc. is the world’s leading multiplexed immunoassay testing laboratory, providing comprehensive protein biomarker services based on its...
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BASi - Bioanalytical Systems, Inc. bioanalytical sample analysis automated in-vivo blood sampling toxicology pharmaceutical analysis electrochemistry EC liquid chromatography LC Vetronics
Dried Blood Spot (DBS)
BASi has emphasized the importance of reducing animal numbers and refining data. We are continuing this tradition as we move forward with utilizing Dried...
GLP Toxicology Services
BASi provides clients with fast, reliable, preclinical in-life and pathological data in compliance with federal guidelines. Clinical pathology, clinical...
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CNBE CNBE is a CRO specialized in low-cost exploratory non-GLP studies in animals. Toxicity, PK and drug efficacy studies in numerous animal models (rodent, rabbit, cotton rats, ferret, minipig/pig, dog, NHP). AAALAC...
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CanAm Bioresearch Inc CanAm Bioresearch is a well-established pharmaceutical contract research organization specializing in pre-clinical discovery and development. We provide bioanalytical, pharmacokinetic, pharmacology, and custom chemical...
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Dow AgroSciences LLC Dow AgroSciences LLC, based in Indianapolis, Indiana, USA, is a top-tier agricultural company that combines the power of science and technology with the "Human Element" to constantly improve what is essential to human...
Entrust® Naturalyte®
Entrust® Naturalyte® insect control knocks out tough pests of organic crops without disrupting populations of most beneficial insects.
HERCULEX®
HERCULEX® XTRA Insect Protection offers the most complete trait option for non-Roundup Ready® acres. It enables top-performing hybrids to reach their...
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Worldwide Primates Worldwide Primates is a leading supplier of premium quality non-human primate models for research, including government, university, and pharmaceutical level facilities.
The company supplies various research model primate...
Capuchins
Worldwide Primates is a leading supplier of premium quality non-human primate models for research, including government, university, and pharmaceutical...
Caribbean and African Green monkeys
Worldwide Primates is a leading supplier of premium quality non-human primate models for research, including government, university, and pharmaceutical...
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Bayer HealthCare AG The Company combines the global activities of the divisions Animal Health, Bayer Schering Pharma, Consumer Care and Medical Care. More than 50,000 people are employed by Bayer HealthCare worldwide. Their aim is to...
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Transposagen Biopharmaceuticals Transposagen Biopharmaceuticals, Inc., a Lexington, KY based company, is the worldwide leader in the creation of unique genetically modified knockout rat models, having created ~95% of the world’s existing inventory. The...
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Sage Labs SAGE Labs has developed a unique portfolio of knockout animals. Our catalog includes knockout rats carrying site-specific deletions in well-established drug transporters - including Mdr1, Mrp1, Mrp2, and Bcrp.
Bcrp Knockout Rat
Novel animal model lacking Bcrp protein. This model is useful in drug transporter assays
Mdr1a Knockout Rat
Novel animal model lacking P-Glyoprotein - making it useful in PK/PD studies.
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Physiogenex CRO in preclinical discovery services for complex metabolic disorders associated with diabetes, liver diseases, lipid disorders and cardiovascular diseases: kinetics with radioctive labelled tracers, nutritional animal...
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Kayungu Chemotherapeutics LTD We are capable of structure-based drug design, hit identification via virtual high screening throughput using docking or 3D and 4D QSAR, lead optimization and chemical synthesis
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More
Animal Pharmacology
Research Library
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Translational Drug Development (TD2)
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Preclinical Case Study: Lead Identification and Optimization
A client created a small-batch panel of novel histone deacetylase inhibitors. The client did not have its own laboratory and had no information on potency, formulation, or overall context of activity of any of the drug candidates.
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Myriad RBM, Inc.
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A 12-Biomarker Multi-Analyte Profile (MAP) for Detecting Kidney Toxicity in Rat Preclinical Drug Studies. Sherry Sours-Brothers, Ph.D. and Dominic Eisinger, Ph.D.
Introduction Rat KidneyMAP® and Biomarker Qualification by the Predictive Safety Testing Consortium Drug induced toxicity is responsible for killing 30% of promising compounds from early preclinical studies and can negatively impact ...
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The Jackson Laboratory
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Floods, tornadoes, fires, and other unforeseen disasters put a monkey wrench in the best of plans, including those of biomedical researchers. It’s only human to think these things won’t happen to us. Unfortunately, they do. Are you prepared?
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CNBE
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Keywords: toxicity, side effects, ingestion, intravenous administration, biodistribution
It is essential to determine the toxicity of nanoparticles prior to its commercialization and its use in humans. The tests required by the regulatory authorities are expensive. It is therefore important to determine early in development the safety thereof. We have developed a model to explore the toxicity of ...
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Rondaxe
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The Food, Drug and Cosmetic Act requires that a drug be the subject of an approved marketing application before it is transported or distributed across state lines. A sponsor however will want to ship an investigational drug to clinical investigators in many states; it must seek an exemption from that legal requirement. The Investigational New Drug Application (IND) obtains this exemption from ...
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Animal Pharmacology
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