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Animal Pharmacology

    
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The Jackson Laboratory  We discover precise genomic solutions for disease and empower the global biomedical community in our shared quest to improve human health. We offer an array of scientific products and services to meet your research needs.
 
Jackson Laboratory Services We are an independent, nonprofit organization focusing on mammalian genetics research to advance human health. Our mission is to discover the genetic basis...
 
Mouse Tissues & Biospecimens Quality organs, fluids, tissues, and embryo products are available from any JAX® Mice strain and customer strains maintained at our facilities. Our highly...
Myriad RBM, Inc.  Myriad RBM is a CLIA-certified biomarker testing laboratory specializing in cost-effective, high-quality multiplexing services. Our protein immunoassays benefit drug discovery & development from preclinical through Phase...
 
RodentMAP® v2.0 A 58-biomarker Multi-Analyte Profile (MAP) focused on the identification of biomarker patterns in rodent biological samples, such as serum or plasma. Myriad...
 
Services Provided Myriad RBM, Inc. is the world’s leading multiplexed immunoassay testing laboratory, providing comprehensive protein biomarker services based on its...
CNBE  CNBE is a CRO specialized in exploratory animal studies: toxicity, PK and drug efficacy studies in numerous animal models (rodents, rabbits, cotton rats, ferrets, farm animals, dogs and non-human primates). CNBE is GAP...
 
CNBE Animal facility description CNBE is GAP (Good Animal Practice) certified and has CCAC and AAALAC accreditations. CNBE has 78 multifunctional animal housing rooms (130,000 sq. ft.) for...
 
CNBE Detailled CRO services CNBE offers turnkey contract research in 1. toxicity (DRF, MTD, NOAEL, NOEL), 2. pharmacokinetic and 3. drug efficacy (proof-of-concept) in many areas...
 
BASi - Bioanalytical Systems, Inc.  bioanalytical sample analysis automated in-vivo blood sampling toxicology pharmaceutical analysis electrochemistry EC liquid chromatography LC Vetronics
 
Dried Blood Spot (DBS) BASi has emphasized the importance of reducing animal numbers and refining data. We are continuing this tradition as we move forward with utilizing Dried...
 
GLP Toxicology Services BASi provides clients with fast, reliable, preclinical in-life and pathological data in compliance with federal guidelines. Clinical pathology, clinical...
CanAm Bioresearch Inc  CanAm Bioresearch is a well-established pharmaceutical contract research organization specializing in pre-clinical discovery and development. We provide bioanalytical, pharmacokinetic, pharmacology, and custom chemical...
Dow AgroSciences LLC  Dow AgroSciences LLC, based in Indianapolis, Indiana, USA, is a top-tier agricultural company that combines the power of science and technology with the "Human Element" to constantly improve what is essential to human...
 
Entrust® Naturalyte® Entrust® Naturalyte® insect control knocks out tough pests of organic crops without disrupting populations of most beneficial insects.
 
HERCULEX® HERCULEX® XTRA Insect Protection offers the most complete trait option for non-Roundup Ready® acres. It enables top-performing hybrids to reach their...
 
Worldwide Primates  Worldwide Primates is a leading supplier of premium quality non-human primate models for research, including government, university, and pharmaceutical level facilities. The company supplies various research model primate...
 
Capuchins Worldwide Primates is a leading supplier of premium quality non-human primate models for research, including government, university, and pharmaceutical...
 
Caribbean and African Green monkeys Worldwide Primates is a leading supplier of premium quality non-human primate models for research, including government, university, and pharmaceutical...
 
Bayer HealthCare AG  The Company combines the global activities of the divisions Animal Health, Bayer Schering Pharma, Consumer Care and Medical Care. More than 50,000 people are employed by Bayer HealthCare worldwide. Their aim is to...
 
Transposagen Biopharmaceuticals  Transposagen Biopharmaceuticals, Inc., a Lexington, KY based company, is the worldwide leader in the creation of unique genetically modified knockout rat models, having created ~95% of the world’s existing inventory. The...
 
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AdaTn(sb-T2/Bart3)2.237Mcwi AdaTn(sb-T2/Bart3)2.237Mcwi
 
Sage Labs  SAGE Labs has developed a unique portfolio of knockout animals. Our catalog includes knockout rats carrying site-specific deletions in well-established drug transporters - including Mdr1, Mrp1, Mrp2, and Bcrp.
 
Bcrp Knockout Rat Novel animal model lacking Bcrp protein. This model is useful in drug transporter assays
 
Mdr1a Knockout Rat Novel animal model lacking P-Glyoprotein - making it useful in PK/PD studies.
 
Physiogenex  CRO in preclinical discovery services for complex metabolic disorders associated with diabetes, liver diseases, lipid disorders and cardiovascular diseases: kinetics with radioctive labelled tracers, nutritional animal...
Kayungu Chemotherapeutics LTD  We are capable of structure-based drug design, hit identification via virtual high screening throughput using docking or 3D and 4D QSAR, lead optimization and chemical synthesis
Biotrofix, Inc.  Biotrofix's mission is to provide the highest-quality preclinical efficacy contract services for CNS, vascular and other diseases to our Clients, who include biotech and pharmaceutical companies, as well as academic...
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More

Animal Pharmacology Research Library

Pathways to Discovery: Autoimmune Diseases
The Jackson Laboratory
There are over 80 autoimmune diseases that affect approximately five to eight percent of the U.S. population. Learn how a pathway resource, designed to facilitate the discovery of new targeted therapies for several autoimmune diseases, will highlight biological pathways diseases share, as well as indicate the most relevant mouse models and resources available for the study.
 
Toxicity evaluation: Nanoparticles
CNBE
Keywords: toxicity, side effects, ingestion, intravenous administration, biodistribution It is essential to determine the toxicity of nanoparticles prior to its commercialization and its use in humans. The tests required by the regulatory authorities are expensive. It is therefore important to determine early in development the safety thereof. We have developed a model to explore the toxicity of ...
 
An Overview of Assay Quality Systems at Rules-Based Medicine
Myriad RBM, Inc.
Stringent guidelines of quality assurance and control (QA/QC) serve as the foundation for dependable and reproducible results in any analytical endeavor. Read step-by-step how the RBM platform combines the sensitivity and dynamic range of microsphere based immuno-multiplexing with the precision and dependability of automated liquid handling.
 
Determination of an Acceptable Preservative for...
BASi - Bioanalytical Systems, Inc.
This method uses a 50:50 THF:water extraction solvent for the preparation of standards and samples. Preservative at a level of 0.1 weight percent in solution was added to stabilize the preparations. Analysis was accomplished by HPLC carried out on a Phenomenex Luna Phenyl Hexyl (150 x 4.6 mm) column at a flow rate of 1.0 mL/min. The separation was completed with a mobile phase of 35 mM ...
 
IND Preparation
Rondaxe
The Food, Drug and Cosmetic Act requires that a drug be the subject of an approved marketing application before it is transported or distributed across state lines. A sponsor however will want to ship an investigational drug to clinical investigators in many states; it must seek an exemption from that legal requirement. The Investigational New Drug Application (IND) obtains this exemption from ...
 

Animal Pharmacology Video

Jackson Laboratory's legacy of genetic discovery The Jackson Laboratory The Jackson Laboratory has been a significant force in genetic discovery for more than 80 years. We discover the genetic basis for preventing, treating ...
 
Research Animal Diagnostic Services Charles River Laboratories International, Inc. Research Animal Diagnostic Services
 
Animal Pharmacology Myriad RBM, Inc. Company

Animal Pharmacology News

Animal Pharmacology BASi - Bioanalytical Systems, Inc. Pharmaceuticals
Animal Pharmacology Wockhardt Company
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