EMD Millipore Bioscience EMD Millipore Bioscience delivers new technologies & workflow solutions that enable researchers to understand complex biological systems & identify new targets.
Diteba Research Laboratories Inc. Diteba is a development and testing laboratory that provides GMP analytical and GLP bioanalytical testing services from pre-clinical to Phase IV testing from method development and validation to QC Release, In Vitro...
Translational Drug Development (TD2) Translational Drug Development (TD2) is a biopharma service provider uniquely positioned to meet your development challenges. TD2 integrates world-class clinical and regulatory expertise with "-omic" science and provides...
Preclinical Services
TD2 provides strong support for the clinical development program by offering innovative preclinical services. TD2 designs and executes in vitro and in vivo...
In Vitro Bioequivalence Analysis
BASi has extensive experience with bioavailability (BA) and bioequivalence (BE) studies. All BA and BE studies are performed in accordance with 21 CFR...
Innogenetics International in vitro diagnostic (IVD) company that develops and markets diagnostic assays in the fields of infectious diseases, genetic testing, transplantation, neurodegeneration, and oncology.
Auto-LIA™ 48
Auto-LIA™ 48 offers fully automated processing for the complete range of INNO-LIA™ tests from sample incubation to color development, ensuring ease, speed,...
Auto-LiPA 48
Auto-LiPA 48 offers fully automated processing for the complete range of INNO-LiPA and INNO-LIA™ tests from hybridization to color development....
CUSTOM ANTIBODY PRODUCTION SERVICES
ProSci Incorporated has produced more than 10,000 custom monoclonal and custom polyclonal antibodies for researchers worldwide in academia, industry,...
Primary Antibodies
ProSci has over 13,000 different antibodies. We have monoclonal and polyclonal antibodies from many different host species including rabbit, mouse, chicken...
The Jackson Laboratory We discover precise genomic solutions for disease and empower the global biomedical community in our shared quest to improve human health. We offer an array of scientific products and services to meet your research needs.
Myriad RBM, Inc. Myriad RBM is a CLIA-certified biomarker testing laboratory specializing in cost-effective, high-quality multiplexing services. Our protein immunoassays benefit drug discovery & development from preclinical through Phase...
Services Provided
Myriad RBM, Inc. is the world’s leading multiplexed immunoassay testing laboratory, providing comprehensive protein biomarker services based on its...
StratiCELL Founded in early 2005, StratiCELL is a leading company assisting the cosmetic, pharmaceutical and chemical industries to the safety and efficacy evaluation of their actives and products by means of in vitro models and...
Genpharmtox.com GenPharmTox stands for quality and safety in risk assessments for drugs and chemicals. As a professional provider for the international chemical, pharmaceutical and biotechnology industries, we meet your demands and those...
ADME in vitro / in vivo
The metabolic stability of the test item is determined using liver
microsomes or primary hepatocytes of different species.The
metabolic stability is also...
The Comet Assay
The comet assay is increasingly used in industrial genotoxicity in vitro. During early
drug development, robust genotoxicity screening assays are required...
International Fertility Medical Center Dr,Ilya Barr,M.D., the founder and the medical director of International Fertility Medical Center, is one of the leading experts in the severe infertility cases and the initiator of advanced infertility and In Vitro...
In Vitro Fertilization
In Vitro fertilization is considered to be one of modern medicine‘s most amazing achievements. In order to reach this treatment stage, some important...
In Vitro Testing Methodologies for Predicting Nasal Drug Absorption and Investigating Factors Influencing Nasal Membrane Permeability and Absorption
Drugs have been administered nasally for therapeutic and recreational purposes since ancient times. In general, among the primary targets for intranasal administration are pharmacologically active compounds with poor stability in gastrointestinal ...
To show that Minncare is effective against other microorganisms, the following in vitro tests were performed using a .5% solution of Minncare. All tests were done on aqueous test solutions at 20°C.
Former Secretary of Defense Donald Rumsfeld once said, “We know what we know, we know that there are things we do not know, and we know that there are things we don’t know we don’t know.” This insight – recognizing the limits of one’s own capacities – may be what separates the true expert from everyone else. Case in point: Raptor Pharmaceutical Corporation acquired orphan compound cysteamine ...
Investigation of the metabolic pathways of new drug candi- dates using both in vitro and in vitro methods has become very important during drug development . The goal of this study was to profile and identify metabolites of apomor- phine, which is under investigation for the treatment of male erectile dysfunction, in both in vitro and in vitro gener- ated samples.
In vitro: The metabolism of ...
A preliminary study was conducted to determine the binding of [14C]warfarin to plasma proteins of human and laboratory animal species and protein solutions using ultrafiltration. [14C]Warfarin was 99.1, 98.9, 97.7, 94.2, 91.9 and 89.1% bound to plasma proteins of human, monkey, rat, rabbit, dog and mouse, respectively (average of the two genders). [14C]Warfarin was highly bound to HAS (99.0%) and ...
Find out how you can optimize your formula for in-process testing, control quality better and avoid lot-to-lot variability and be in full compliance with SUPAC and FDA guidelines for pre and post-change formulations, manufacturing site transfers, using skin penetration studies for BA/BE evaluations and interpreting the data generated for SUPAC submissions.
The identification and application of correlates of immune response can enable significant time and money savings especially in clinical trial settings for vaccine and biologic R&D. Functional cell-mediated immune response assays have been used as readouts · To evaluate efficacy of vaccines and therapeutic strategies for infectious diseases and cancer · To identify and characterize the undesired ...
Phase I Study Start-up: Working within tight timelines
A client presented with a compound ready for a Phase I "First-in-man" study. The client had a Board-imposed deadline to submit their Investigational New Drug (IND) Application within two months and needed a Phase I protocol written and finalized to submit with the IND. Additionally, the client needed at least one site up and running within ...
A 12-Biomarker Multi-Analyte Profile (MAP) for Detecting Kidney Toxicity in Rat Preclinical Drug Studies. Sherry Sours-Brothers, Ph.D. and Dominic Eisinger, Ph.D.
Introduction Rat KidneyMAP® and Biomarker Qualification by the Predictive Safety Testing Consortium Drug induced toxicity is responsible for killing 30% of promising compounds from early preclinical studies and can negatively impact ...
This eBook is based on articles from Diteba's Blog and excerpts from the whitepaper "An Alternative Approach to Bioequivalence Studies for Semi- Solid Dosage Form Products". You will read insights from Diteba's Chief Scientific Officer and Executive Vice President of Science, Dr. Theo Kapanadze, D.Sc., Ph.D.
Dr. Kapanadze has extensive knowledge and experience in this realm of study. He has ...
Explore Diteba's Laboratory Testing capabilities and find out how we can help you turn your research into reality and expedite the process of bringing ...
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