Rules-Based Medicine Rules-Based Medicine (RBM) is a CLIA-certified biomarker testing laboratory specializing in cost-effective, high-quality multiplexing services. Our protein immunoassays benefit drug discovery & development from...
The Jackson Laboratory We help researchers discover treatments, preventions and cures for human disease through the provision of inbred, mutant and genetically engineered mouse models, research services, and comprehensive technical information...
GenScript USA Inc GenScript is a leading biology CRO focusing exclusively on early drug discovery and development services. Built on our assembly-line mode, one-stop solution, continuous improvement, and stringent IP protection, GenScript...
Molecular Devices, Inc. Molecular Devices, Inc. supplies high-performance analytical systems, including instruments, software, and reagents, to accelerate and improve drug discovery and basic life science research. By providing systems that...
Lancaster Laboratories Lancaster Laboratories is the trusted leader in biopharmaceutical and pharmaceutical laboratory services and scientific solutions.
Biochemistry
We offer a comprehensive range of services to support biopharmaceutical development from routine testing to the complete characterization of proteins,...
Biopharmaceutical Services
Lancaster Laboratories provides a broad range of laboratory services supporting the biopharmaceutical industry. These services include cell and molecular...
Cell Bank Manufacturing
Lancaster Laboratories offers capabilities to manufacture, store and characterize a wide variety of mammalian cell banks, including master, working and...
BioReliance BioReliance Corporation has more than 60 years of experience working with healthcare companies and government agencies to support the development and manufacture of safe and effective products.
BioReliance is the largest...
Cell Bank Manufacturing
BioReliance is dedicated to meeting your manufacturing needs for the production of mammalian and insect cell banks. Our cGMP production facilities and...
Process variability is a leading cause in biopharmaceutical batch failure and impacts the value and profitability of the industry. Thermo Fisher Scientific controls inherent variability through the use of the Thermo Scientific Antaris line of Fourier transform near-infrared (FT-NIR) spectrometers.
AMSBIO have announced a range of ready-to- use lentivirus supernatant products suitable for many kinds of gene delivery applications including mammalian protein expression, stable cell line construction, cell signal pathway localization and stem cell research.
Converting fully differentiated mouse or human somatic cells into embryonic-like cells (so called induced Pluripotent Stem Cell: iPSC) ...
Epidemiologic analysis has revealed the association of psoriasis with inflammatory bowel disease (IBD) in humans. In mice, transfer of CD45RBhi CD4+ naive T cells into immunodeficient animals induces colitis and psoriasis-like phenotypes. This sample study describes the utility of such an adoptive transfer model to evaluate novel compounds for the treatment of IBD and psoriasis.
Purpose: To compare the transport of six b-adrenergic receptor antagonists tested individually or combined (“N-in-one”) across Caco-2 cell monolayers prepared by either the Biocoat® 3 to 5-day culture method or the standard 21-day culture method.
Methods: Caco-2 cell monolayers were cultured using either the Biocoat® 3 to 5-day, or the standard 21-day methods. Monolayers prepared with the ...
Pre-Market Testing for Cosmetic and Personal Care Products Requirements for Safety Efficacy and Maintaining Product Integrity
By Bradford Rope, President BioScreen Testing Services, Inc. What could be more important than protecting your trademark and good name of your company? Anyone can purchase a formula in a bottle, but the knowledge of how to protect your investment can make or break your ...
The risk of virus contamination is a feature common to all biotechnology products produced from animal or human sources. Contamination can arise from a source cell line or from adventitious virus introduced during production. The approach to ensuring viral safety includes several complementary approaches, which are laid out in guidelines from the FDA, EMEA and ICH (references 1-4). These ...
With the global economy in a recession, a vast majority of pharma- ceutical companies are being forced to cut costs and control spending. For most companies this means a reduction in workforce and tighter outsourcing budgets. Companies are left with the same amount of required laboratory testing, but with fewer employees to perform the work in-house. Clients are left searching for value-added ...
Lancaster Laboratories' Professional Scientific Staffing service has been specifically designed to give you the “non-permanent” workforce you need for anywhere from one year to 10 years or more with no worries about co-employment and at lower costs than fixed headcounts.
Companies have traditionally used two types of staff: their own employ-ees and a temporary workforce. In today's economic ...
Formulation is arguably the most critical—and challenging—component of biopharmaceutical drug development, second only to the molecule itself. Formulation's far-reaching consequences help sponsors satisfy the scientific, medical, and regulatory conditions for drug approval and, subsequently, support marketplace success.
A biopharmaceutical formulation consists of active pharmaceutical ...
Caco-2 cells are a widely used in vitro model for studies involving the transepithelial transport of potential drug candidates. The purpose of this study was to compare the transport characteristics of six compounds, all beta- adrenergic receptor antagonists, both individually and combined (“N-in-one”) across Caco-2 cell monolayers. Caco- 2 cells were cultured on Costar Transwell inserts in ...
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