Rules-Based Medicine Rules-Based Medicine (RBM) is a CLIA-certified biomarker testing laboratory specializing in cost-effective, high-quality multiplexing services. Our protein immunoassays benefit drug discovery & development from...
The Jackson Laboratory We help researchers discover treatments, preventions and cures for human disease through the provision of inbred, mutant and genetically engineered mouse models, research services, and comprehensive technical information...
DNA 2.0 Inc DNA2.0 is a privately-held, leading synthetic genomics company, headquartered in Menlo Park, CA. It is the largest US provider of synthetic genes, with a global customer base comprised of academia, government and the...
Gene Synthesis
Synthetic genes are genetic material created to provide an immediate and easy path from sequence databases and sequence manipulation software to physical...
EPICENTRE
EPICENTRE Biotechnologies, founded in 1987, is a manufacturer and seller of high-quality molecular biology products for life science research, clinical research, molecular diagnostics and biopharmaceutical...
Clongen Laboratories, LLC Clongen Labs focuses on using rapid detection methods such as PCR, Real Time PCR and DNA sequencing for identification of human and animal pathogens. One of our main strengths is assay development and we have been able...
Ensemble Discovery Corporation Ensemble Discovery is investigating the drug discovery potential of Ensemblins, orally bioavailable small molecule macrocyclic compounds that have the potential to behave like biologics and can disrupt protein-protein...
Telomerase is a specialized ribonucleoprotein composed of telomerase reverse transcriptase (TERT), an intrinsic RNA template (TR), and several associated proteins. Its main function is to stabilize telomeres, which protect chromosomes from recombination and end-to-end fusion.
Telomeres also recognize DNA damage and control the replicative capability of cells. With each cell division some of ...
Cyclooxygenases (COXs), also known as prostaglandin H synthases, are fatty acid oxygenases that contain about 600 amino acid residues and act on arachidonic acid to generate prostaglandins (PG). All vertebrates contain two COX genes: one encoding the constitutive COX-1 and another inducible COX-2. COX-1 and COX-2 share approximately 60-65% amino acid identity. These COX isoforms are bifunctional ...
Build a Strong Research Foundation with Quality Tools.
As an affiliate of Merck KGaA, Darmstadt, Germany, EMD Chemicals offers over 300 years of expertise and a wide range of Molecular Biology Grade research essentials that give you a firm foundation to build your research on.
Effcient, nonselective methods to obtain DNA from the environment are needed for rapid and thorough analysis of introduced microorganisms in environmental samples and for analysis of microbial community diversity in soil. A small-scale procedure to rapidly extract and purify DNA from soils was developed for in-the-eld use. Amounts of DNA released from bacterial vegetative cells, bacterial ...
AMSBIO have announced a range of ready-to- use lentivirus supernatant products suitable for many kinds of gene delivery applications including mammalian protein expression, stable cell line construction, cell signal pathway localization and stem cell research.
Converting fully differentiated mouse or human somatic cells into embryonic-like cells (so called induced Pluripotent Stem Cell: iPSC) ...
Transforming growth factor- (TGF-), a member of the TGF superfamily of proteins that includes activins, inhibins, and bone morphogenetic proteins (BMPs), regulates a wide array of cellular processes including cell differentiation, cellular senescence, immune response, wound healing, and apoptosis. TGF- signaling promotes growth and development during early embryogenesis. However, in mature ...
The identification of fungi, especially filamentous fungi, has historically been a very difficult task. Due to the amount of experience required to accurately identify filamentous fungi to the species level, it has become acceptable to either identify these organisms to the genus level, or in some cases, simply identify them as “molds.” Over the years, there have been numerous attempts to ...
Environmental monitoring programs require the rapid and accurate Environmental monitoring programs require the rapid and accurate id of microorganisms. Fungal species are typically identification f iiFl i til tifi ti identified microscopically or by sequencing the D1 D2 region of the py y qg g identified microscopically or by sequencing the D1-D2 region of the large ribosomal subunit and ...
In unstressed cells, p53 is latent and is maintained at low levels by targeted degradation mediated by MDM2. Through its binding to p53, MDM2 can shuttle p53 out of the nucleus into the cytoplasm for degradation. When normal mammalian cells are subjected to stress signals, such as hypoxia, radiation, and chemotherapeutic drugs, p53 is phosphorylated at multiple sites, including those involved in ...
To identify bacteria and fungi, pharmaceutical manufactures rely on curated, compliant and up-to-date libraries. Results of using a proprietary library, based on over 300,000 unknown organisms recovered from environmental monitoring programs, show a two-fold reduction in unidentified strains when compared to a commercially available library.
The miVac Duo is suitable for use with a wide range of solvents, from volatile organic solvents through to water and some of the higher boiling point ...
The MICROLAB® NIMBUS is Hamilton Company's newest automated multi-channel pipetting platform, offering a high density deck layout in a body small enough ...
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