Rules-Based Medicine Rules-Based Medicine (RBM) is a CLIA-certified biomarker testing laboratory specializing in cost-effective, high-quality multiplexing services. Our protein immunoassays benefit drug discovery & development from...
The Jackson Laboratory We help researchers discover treatments, preventions and cures for human disease through the provision of inbred, mutant and genetically engineered mouse models, research services, and comprehensive technical information...
PrimeSyn Lab Inc. PrimeSyn Lab, Inc. (PSL) is a recognized leader in the area of Custom Oligos / GMP Oligos and specializes in ULTRA PURE DNA Synthesis and Analyte Specific Reagent (ASR) primers, long oligos (100-150 base pairs) and...
Genomics Collaborative BioServe provides a comprehensive 'biomaterial to validated data' genomics services platform, helping researchers gain the pre-clinical data for breakthroughs in drug discovery, molecular diagnostics and pharmacogenomics....
DNA 2.0 Inc DNA2.0 is a privately-held, leading synthetic genomics company, headquartered in Menlo Park, CA. It is the largest US provider of synthetic genes, with a global customer base comprised of academia, government and the...
Bio Synthesis BIO-SYNTHESIS, INC., founded in 1984, has provided design and delivery for reliable and innovative molecular biology services and products such as custom oligonucleotide, custom peptides ,custom antibody, and custom...
Custom DNA Synthesis
Bio-Synthesis, the first company to provide commercial custom DNA synthesis services, has remained a major force in advancing biotechnology research both as...
Build a Strong Research Foundation with Quality Tools.
As an affiliate of Merck KGaA, Darmstadt, Germany, EMD Chemicals offers over 300 years of expertise and a wide range of Molecular Biology Grade research essentials that give you a firm foundation to build your research on.
Cyclooxygenases (COXs), also known as prostaglandin H synthases, are fatty acid oxygenases that contain about 600 amino acid residues and act on arachidonic acid to generate prostaglandins (PG). All vertebrates contain two COX genes: one encoding the constitutive COX-1 and another inducible COX-2. COX-1 and COX-2 share approximately 60-65% amino acid identity. These COX isoforms are bifunctional ...
AMSBIO have announced a range of ready-to- use lentivirus supernatant products suitable for many kinds of gene delivery applications including mammalian protein expression, stable cell line construction, cell signal pathway localization and stem cell research.
Converting fully differentiated mouse or human somatic cells into embryonic-like cells (so called induced Pluripotent Stem Cell: iPSC) ...
Diethyl oxalate is an important molecule with various applications including: total synthesis,1 biochemistry,2 materials science,3 and combinatorics.4 While unlabeled diethyl oxalate is commercially available5 and its synthesis has been reported,6 few attempts have been made to synthesize isotopically labeled (i.e. 13C or 14C diethyl oxalate). Furthermore, the few reported syntheses of 13C and ...
Synthesis of [14C]-2,6-pyridinedicarboxaldehyde (2) used Selective superoxide dismutase (SOD) mimetics are commercially available 6-bromopicolinic acid as starting potentially useful in pathol. conditions in which there is an material. The 6-bromopicolinic acid was protected as a methyl overproduction of superoxide anion O2-. These conditions ester using refluxing methanol in the presence of ...
Transforming growth factor- (TGF-), a member of the TGF superfamily of proteins that includes activins, inhibins, and bone morphogenetic proteins (BMPs), regulates a wide array of cellular processes including cell differentiation, cellular senescence, immune response, wound healing, and apoptosis. TGF- signaling promotes growth and development during early embryogenesis. However, in mature ...
The identification of fungi, especially filamentous fungi, has historically been a very difficult task. Due to the amount of experience required to accurately identify filamentous fungi to the species level, it has become acceptable to either identify these organisms to the genus level, or in some cases, simply identify them as “molds.” Over the years, there have been numerous attempts to ...
Telomerase is a specialized ribonucleoprotein composed of telomerase reverse transcriptase (TERT), an intrinsic RNA template (TR), and several associated proteins. Its main function is to stabilize telomeres, which protect chromosomes from recombination and end-to-end fusion.
Telomeres also recognize DNA damage and control the replicative capability of cells. With each cell division some of ...
To identify bacteria and fungi, pharmaceutical manufactures rely on curated, compliant and up-to-date libraries. Results of using a proprietary library, based on over 300,000 unknown organisms recovered from environmental monitoring programs, show a two-fold reduction in unidentified strains when compared to a commercially available library.
In unstressed cells, p53 is latent and is maintained at low levels by targeted degradation mediated by MDM2. Through its binding to p53, MDM2 can shuttle p53 out of the nucleus into the cytoplasm for degradation. When normal mammalian cells are subjected to stress signals, such as hypoxia, radiation, and chemotherapeutic drugs, p53 is phosphorylated at multiple sites, including those involved in ...
The miVac Duo is suitable for use with a wide range of solvents, from volatile organic solvents through to water and some of the higher boiling point ...
The MICROLAB® NIMBUS is Hamilton Company's newest automated multi-channel pipetting platform, offering a high density deck layout in a body small enough ...
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