Rules-Based Medicine Rules-Based Medicine (RBM) is a CLIA-certified biomarker testing laboratory specializing in cost-effective, high-quality multiplexing services. Our protein immunoassays benefit drug discovery & development from...
amsbio AMS Biotechnology, Leader in developing modern products and technologies for life science research: Antibody, Protein, Peptide, Apoptosis, Migration, Cell Proliferation kits and reagents, Cytokines, Protein Kinases,...
The Jackson Laboratory We help researchers discover treatments, preventions and cures for human disease through the provision of inbred, mutant and genetically engineered mouse models, research services, and comprehensive technical information...
Asterand, plc Asterand plc is the leading global supplier of high quality, well characterized human tissue and human tissue-based research services to pharmaceutical and biotechnology companies engaged in drug discovery research.
World BioBank World BioBank provides industry and academia genetically diverse, high quality, standardized biospecimens with high quality data. Services also include biomarker storage, management and consultation for clinical trials...
LIQUID TISSUES
• Peripheral blood
• Genomic DNA (from buffy coat)
• Plasma
• Serum
Capital Biosceinces Capital Biosciences, Inc. offers a variety of biological products including Cell Immortalization Products, Clinically Defined Human Tissue, cDNA ORF Clones, Premade Adenoviruses, Purified Proteins, Viral Expression...
Accumbens- left, Normal FFPE tissue
CBI provides normal human tissue from a clinically-unremarkable donor. Preparation: FFPE block. Tissue is prepared by a certified medical pathologist, fixed...
Accumbens- left, Normal OCT frozen tissue
CBI provides normal human tissue from a clinically-unremarkable donor. Preparation: OCT embedded tissue (one block) prepared by a certified histologist....
Accumbens- left, Normal snap-frozen tissue
CBI provides normal human tissue from a clinically-unremarkable donor. Preparation: snap-frozen tissue. Tissue (0.5 -1 gram) is prepared by a certified...
A sensitive, simultaneous and rugged LC-MS/MS method was developed and validated for the quantitation of cortisol and 6ß-hydroxycortisol in human urine. Changes in ratio of 6ß-hydroxycortisol/cortisol in response to a drug is an indi- cation of induction/inhibition of CYP3A enzymes.
Calibration curves and QC samples were prepared in a surrogate matrix. Endogenous levels, recovery of spiked ...
Erythromycin is a known CYP3A4 inhibitor and is used in the investigation of potential drug-drug interactions in clinical studies.1 A specific HPLC-MS/MS assay method for the determination of erythromycin in human plasma was developed and validated according to the current industry guidelines.2
Erythromycin is a known CYP3A4 inhibitor and is used in the investigation of potential drug-drug interactions in clinical studies.1 A specific HPLC-MS/MS assay method for the determination of erythromycin in human plasma was developed and validated according to the current industry guidelines.
Introduction/Objectives:
-J867 is a novel selective progesterone receptor modulator (SPRM).
-Investigate the in vitro metabolism of J867 using hepatocytes and liver microsomes from male and femal human and various animal species.
-Characterize radioactivity in microsome and hepatocyte metabolites using HPLC-radiochromatography.
-Tentatively identify J867 metabolites by LC-MS/MS generated ...
Amlexanox is used in the treatment of minor aphthous ulcers (canker sores). A specific HPLC-FL assay method for the determination of amlexanox in human serum was therefore developed and validated according to the current industry guidelines.1 The calibration range for the method is 5-250 ng/mL.
AMSBIO have announced a range of ready-to- use lentivirus supernatant products suitable for many kinds of gene delivery applications including mammalian protein expression, stable cell line construction, cell signal pathway localization and stem cell research.
Converting fully differentiated mouse or human somatic cells into embryonic-like cells (so called induced Pluripotent Stem Cell: iPSC) ...
LC-MS/MS and ICP-AES methods were developed and validated for the quantitation of Gadoversetamide (MP-1177) in human plasma. For LC-MS/MS, human plasma containing MP-1177 and the internal standard, MP-2077, was subjected to ultrafiltration.The filtrates were analyzed directly.
LC-MS/MS and ICP-AES methods were developed and validated for the quantitation of Gadoversetamide (MP-1177) in human urine. For LC-MS/MS, human urine containing MP-1177 and the internal standard, MP-2077, was centrifuged.The supernatant was analyzed directly. For ICP-AES, human urine containing MP-1177 was acidified with HCl and analyzed directly for gadolinium.
The objective was to validate a sensitive and specific HPLC-MS/MS assay to determine the concentration of PL-2299 in human, rat and beagle plasma for support of Palatin Technologies, Inc. preclinical and clinical studies.
Budesonide is an anti-inflammatory, synthetic corticosteroid used for the treatment of asthma by oral inhalation.The objective was to validate a sensitive and specific HPLC-MS/ MS assay to determine budesonide in human plasma for support of Sheffield Pharmaceutical clinical trials. An automated 96-well HPLC-MS/MS assay method for the determination of budesonide in human plasma was therefore ...
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