Rules-Based Medicine Rules-Based Medicine (RBM) is a CLIA-certified biomarker testing laboratory specializing in cost-effective, high-quality multiplexing services. Our protein immunoassays benefit drug discovery & development from...
Rat KidneyMAP
The RBM Rat KidneyMAP™ detects early signs of renal damage which is a common problem in drug development programs. Developed in conjunction with the...
Rat MetabolicMAP
A 21-biomarker Multi-Analyte Profile (MAP) designed by a major pharmaceutical company to identify metabolic biomarker patterns in rat biological samples,...
RodentMAP
A 58-biomarker Multi-Analyte Profile (MAP) focused on the identification of biomarker patterns in rodent biological samples, such as serum or plasma. RBM's...
The Jackson Laboratory We help researchers discover treatments, preventions and cures for human disease through the provision of inbred, mutant and genetically engineered mouse models, research services, and comprehensive technical information...
Aged Mice
In some mouse models, a disease condition develops only with age. JAX will maintain your research strain, or any JAX® Mice strain, and deliver mice to you...
Cancer Services
JAX® In Vivo Services cancer program provides highly customizable preclinical oncology services to help customers evaluate novel anticancer therapies. We...
Compound Evaluation
We have expertise with a variety of therapeutic areas, including atherosclerosis, cancer, diabetes and obesity, inflammatory bowel disease,...
The Integra Group The Integra Group is a full-service clinical and preclinical research organization that produces timely results through an integrated approach and unique partnerships with clients. Committed to providing comprehensive...
ABC Laboratories ABC Laboratories is a drug development partner that understands what you need from an outsourcing relationship: technical expertise, effective communication and on-time, reliable results. With recent investments in...
ABC Bioanalytical Method Development
ABC's bioanalytical team has developed and validated over 150 proprietary methods for preclinical and clinical programs, and has experience with 25 drug...
ABC Bioanalytical Testing
ABC Laboratories offers dose formulation and routine bioanalytical testing for preclinical through Phase III clinical trials. Our bioanalytical team has...
ABC CGMP Radiolabeling & Synthesis
Few contract research laboratories maintain the rigorous CGMP-compliant environment required to produce certified radiolabeled product suitable for human...
Epidemiologic analysis has revealed the association of psoriasis with inflammatory bowel disease (IBD) in humans. In mice, transfer of CD45RBhi CD4+ naive T cells into immunodeficient animals induces colitis and psoriasis-like phenotypes. This sample study describes the utility of such an adoptive transfer model to evaluate novel compounds for the treatment of IBD and psoriasis.
Conducting comprehensive metabolism studies has long been an essential component of a preclinical drug development program. However, numerous factors — including the increased development of protein-derived drugs and the expanded interest in the role of metabolites in safety assessment — are having a significant impact on the regulatory mandates, scope of studies and methodologies employed. In ...
In March 2006, six normal healthy volunteers par- ticipating in a clinical study in the UK were given an intravenous (IV) dose of an experimental immunother- apeutic as a part of an ascending single dose safety and tol- erability study. Within a few hours of drug administration, all subjects exhibited severe reactions which progressed to multiple organ failure. As a result of the incident, ...
The approval by the Food and Drug Administration (FDA) of the first inhaled insulin combination product for treatment of diabetes represents a milestone in drug delivery. Exubera is an inhaled powder form of recombinant human insulin (rDNA) used in the treatment of adult patients with type 1 and type 2 diabetes and is the first new delivery option introduced since the discovery of insulin in the ...
Biotech was “born” in the 1970s. Since that time innovation by biotech pioneers has brought more than 200 medicines and vaccines to fruition for difficult-to-treat indications including oncology, HIV/ AIDs, diabetes, and immune disorders.
Biotech is poised to capitalize on the current challenges confronting Big Pharma: looming patent expirations on blockbuster medicines and a dearth of new ...
Company descriptions and contact
information are quoted
from the company's website or other promotional information. JAZ'D is not responsible for
the accuracy
of this information. Unless specifically noted, JAZ'D is not sponsored by, affiliated with
or otherwise
connected with any of the listed companies.
