Rules-Based Medicine Rules-Based Medicine (RBM) is a CLIA-certified biomarker testing laboratory specializing in cost-effective, high-quality multiplexing services. Our protein immunoassays benefit drug discovery & development from...
The Jackson Laboratory We help researchers discover treatments, preventions and cures for human disease through the provision of inbred, mutant and genetically engineered mouse models, research services, and comprehensive technical information...
Aged Mice
In some mouse models, a disease condition develops only with age. JAX will maintain your research strain, or any JAX® Mice strain, and deliver mice to you...
Cryopreserved Mouse Embryos
Each embryo shipment contains enough embryos to recover a minimum of two pairs of mice, one mouse of each pair being a carrier animal. A detailed recovery...
Cryorecovery
Sperm Cryorecovery
Sperm cryopreservation using the published JAX method enables strains to be quickly, reliably and cost-effectively recovered. A standard...
Taconic Taconic is dedicated to developing and delivering animal models and related laboratory services for the biomedical research community. We work closely with researchers to assure the integrity of their studies by...
Transposagen Biopharmaceuticals Transposagen is the worldwide leader in the creation of unique genetically modified knockout rat models. Over 100 TKO knockout rat lines have been created including the world's first SCID rat. TKO Knockout Rats are used...
piggyBac iPS Technology
piggyBac has other applications including reprogramming fibroblasts to induced pluripotent stem (iPS) cells. These non-embryonic stem cells share most of...
TGEM Rat Models
Laboratory rats with a genetic mutation not created by a gene trap insertion.
TKO Knockout Rat Models
Laboratory rats with a single gene trap insertion created using mobile DNA technology
Capital Biosceinces Capital Biosciences, Inc. offers a variety of biological products including Cell Immortalization Products, Clinically Defined Human Tissue, cDNA ORF Clones, Premade Adenoviruses, Purified Proteins, Viral Expression...
1 iLent-EGFP Construct
1 iLenti-EGFP Construct- Ready for Transfection
Custom-made, Ready-to-use Lenti-RNAi for transfection or infection
Advantages of i-Lenti RNAi:
*RNAi in...
1 iLenti Construct
1 iLenti Construct- Ready for Transfection
Custom-made, Ready-to-use Lenti-RNAi for transfection or infection
Advantages of i-Lenti RNAi:
>RNAi in...
Kent Scientific For over 20 years, Kent Scientific Corporation has been serving medical and research scientists as a worldwide provider of integrated solutions for pre-clinical research and drug discovery advancement. You can choose from...
Embark Scientific Embark Scientific provides Clinical and Pre-clinical Assay Development, High throughput Sample Processing, Laboratory Animal Genetics, mouse genotyping and Health Monitoring, Research-based development and testing...
Inflammation and Neurology Discovery Services
Discovering or confirming how and where your compound acts upon the adaptive immune response can reduce late phase failures and expand the potential utility of your therapy.
Drug Discovery Challenge Drug discovery is a long and time-consuming process. Pharmaceutical companies are under constant pressure to fill their product pipelines, decrease the ...
In March 2006, six normal healthy volunteers participating in a clinical study in the UK were given an intravenous (IV) dose of an experimental immuno therapeutic as a part of an ascending single dose safety and tolerability study. Within a few hours of drug administration, all subjects exhibited severe reactions which progressed to multiple organ failure. As a result of the incident, regulatory ...
This pathways resource is designed to facilitate the discovery of new targeted therapies for several common human autoimmune diseases by highlighting the biological pathways they share and the most relevant mouse models and resources available for their study. Inside, you will find the following:
• Schematics of the genetic pathways common to rheumatoid arthritis, asthma, psoriasis, multiple ...
The feasibility of reversing human aging within a matter of decades has traditionally been dismissed by all profes- sional biogerontologists, on the grounds that not only is aging still poorly understood, but also many of those aspects that we do understand are not reversible by any current or foreseeable therapeutic regimen. This broad consensus has recently been challenged by the publica- tion, ...
Biotech was “born” in the 1970s. Since that time innovation by biotech pioneers has brought more than 200 medicines and vaccines to fruition for difficult-to-treat indications including oncology, HIV/ AIDs, diabetes, and immune disorders.
Biotech is poised to capitalize on the current challenges confronting Big Pharma: looming patent expirations on blockbuster medicines and a dearth of new ...
The purpose of this document is to recommend international standards for and to promote harmonization of the nonclinical safety studies needed to support human clinical trials of a given scope and duration. Harmonization of the guidance for nonclinical safety studies will help to define the current recommendations and reduce the likelihood that substantial differences will exist between regions. ...
The competitive pressure to manage complexity and uncertainty in clinical trials has never been greater. To successfully forecast and manage clinical ...
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