Drucker Co. As a leading supplier and pioneer of quality centrifuges since 1932, The Drucker Company continues to provide state-of-the-art technology in every product we offer. Every day, our centrifuges are being used in virtually...
Special Projects International Special Projects International, Inc. buys, sells, consigns and brokers quality surplus processing and packaging machinery for the chemical and food industries.
DEACOM Deacom's pharmaceutical ERP software is the complete manufacturing ERP software system for pharmaceutical manufacturers. Security specialized to insure data integrity and prevent data corruption in one pharmaceutical...
Beckman Coulter, Inc. Beckman Coulter, Inc. is a leading manufacturer of biomedical testing instrument systems, tests and supplies that simplify and automate laboratory processes. Spanning the biomedical testing continuum—from pioneering...
Airfuge® Ultracentrifuge
With the ability to provide a simple, rapid method of removing chylomicrons (fat particles in lipemic samples), the Airfuge CLS delivers accurate results...
Optima™ L-100 K Preparative Ultracentrifuge
Unmatched versatility, reliability and safety.
Capable of generating 802,000 x g at speeds up to 100,000 rpm, Beckman Coulter's Optima L-100 K...
Optima™ L-90 K Preparative Ultracentrifuge
Capable of generating 694,000 x g at speeds up to 90,000 rpm, the Optima L-90 K Ultracentrifuge enables you to perform more separations in less time. This...
Cole-Parmer Instrument Co. Since 1955, Cole-Parmer has been a leading global source of laboratory and industrial fluid handling products, instrumentation, equipment, and supplies. We are proven experts in the fields of temperature measurement and...
Pharmaceutical manufacturing executives today are all too familiar with industry regulations such as Title 21 CFR Part 11 and current good manufacturing practices (cGMPs). However, many drug companies still struggle to comply with these and other U.S. Food and Drug Administration (FDA) requirements.
In 2008 alone, the FDA issued 43 warning letters to pharmaceutical companies for regulatory ...
Cyclooxygenases (COXs), also known as prostaglandin H synthases, are fatty acid oxygenases that contain about 600 amino acid residues and act on arachidonic acid to generate prostaglandins (PG). All vertebrates contain two COX genes: one encoding the constitutive COX-1 and another inducible COX-2. COX-1 and COX-2 share approximately 60-65% amino acid identity. These COX isoforms are bifunctional ...
In unstressed cells, p53 is latent and is maintained at low levels by targeted degradation mediated by MDM2. Through its binding to p53, MDM2 can shuttle p53 out of the nucleus into the cytoplasm for degradation. When normal mammalian cells are subjected to stress signals, such as hypoxia, radiation, and chemotherapeutic drugs, p53 is phosphorylated at multiple sites, including those involved in ...
Telomerase is a specialized ribonucleoprotein composed of telomerase reverse transcriptase (TERT), an intrinsic RNA template (TR), and several associated proteins. Its main function is to stabilize telomeres, which protect chromosomes from recombination and end-to-end fusion.
Telomeres also recognize DNA damage and control the replicative capability of cells. With each cell division some of ...
Transforming growth factor- (TGF-), a member of the TGF superfamily of proteins that includes activins, inhibins, and bone morphogenetic proteins (BMPs), regulates a wide array of cellular processes including cell differentiation, cellular senescence, immune response, wound healing, and apoptosis. TGF- signaling promotes growth and development during early embryogenesis. However, in mature ...
Watch this video to investigate high performance fume hoods. The innovative and aerodynamic designs of the sash handle, air foil, upper dilution air ...
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