Tosoh Bioscience Tosoh Bioscience manufactures columns, resins and instruments for the liquid chromatography market. With over 30 years of experience our company is recognized as a leader in the HPLC arena with columns and resins for all...
ChainLink Research, Inc. The company was founded in the year 2003.ChainLink Research has quickly established its growing influence and thought leadership in Supply Chain Management.The company is one of the most widely respected Research and...
Werum Software & Systems America, Inc. Werum Software & Systems is the worldwide leading supplier of Manufacturing Execution Systems (MES) for the pharmaceutical and biopharmaceutical industries.In December 2000, Werum founded Werum America, Inc. in...
Xyntek Incorporated Xyntek, Inc. was founded in 1986 by a group of Real-Time Automation & System Solution Engineers. Xyntek, Inc. is a Global Leader in Real-Time IT and Industrial Automation solutions. Xyntek, Inc. continues to be one of...
Commercially available sub-2µm or sub-3µm particle columns have been used to shorten analytical time in a wide range of fields. Columns with such smaller particles improve separation efficiency and allow use of shorter columns and higher linear velocity without compromising the separation. In particular, sub-3µm columns such as 2.2µm particle columns provide similar separation efficiency to ...
Size exclusion chromatography (SEC) is a chromatographic method in which particles are separated based on their hydrodynamic vol- ume. When the separation medium is a gel, the technique is known as gel permeation chroma- tography (GPC) or gel filtration chromatogra- phy (GFC). Often the terms SEC and GPC are used interchangeably, while GFC is most often used for aqueous chromatography. ...
UHPLC often provides run times of less than one minute with peak widths of less than 200 milliseconds, which have created challenges for system performance and detection methods. A variety of applications in the pharmaceutical and environmental areas, using small particle columns, is presented to demonstrate the throughput and performance of the new Nexera UHPLC.
Ribavirin is an antiviral prodrug used for the treatment of Hepatitis C and respiratory syncytial virus (RSV) among other common viruses. A method for the analysis and quantification of ribavirin in rat plasma utilizing HPLC-MS/MS with updated HPLC column technology has been developed and validated according to the FDA guidance to the industry.
The assay displays good linearity with ...
Purpose. In order to increase the sample throughput of a manual LC-FL assay for ketoconazole, the method was automated and a multiplexed HPLC system was employed.
Methods. The original ketoconazole method involved manual protein precipitation, followed by HPLC-FL analysis with a run time of approximately 15 minutes. The sample preparation was converted to the 96 well format and automated using ...
Enoximone is a selective PDE-3 inhibitor currently in Phase III development for the treatment of advanced chronic heart failure. Enoximone is metabolized to the primary metabolite, enantiomeric enoximone sulfoxide, and it is important to determine if this conversion is stereoselective.
The first time synthesis of L-Cyclohexylglycine- [ring-d11] (L-CHG-d11) and L-Cyclohexylglycine-[1-14C] (L-CHG-1-14C) are described.The resolution of DL-Cyclohexylglycine- [ring-d11] and [1-14C] are achieved by enzymatic process. The chiral purity was determined by converting L-Cyclohexylglycine to Cbz-L-cyclohexylglycine and then checked by chiral HPLC.
L-Cyclohexylglycine-[ring-d11] and ...
Thermo Scientific FAST GC columns will save you time and money by utilizing state-of-the-art technology available in modern GC's.
Ability to deliver equivalent resolution compared with conventional length and diameter columns in shorter analysis times.
The major advantage of FAST GC columns is their ability to deliver equivalent resolution compared with conventional length and diameter columns ...
Rapid, Sensitive, General-Purpose Cleaning-Verification HPLC Methods Using Fused-Core™ Particle (FCP) Columns on Conventional Instrumentation S. Bannister1, M. Talbott1, F. Hanciles1, R. Henry2 1Xcelience LLC, Tampa, FL; 2Consultant, State College, PA
This work was undertaken to investigate the use of rapid gradients using recently introduced FCP columns on conventional instrumentation in the ...
Recent industry analyst reports predict that worldwide pharmaceutical industry revenues will grow at a compound annual growth rate (CAGR) of 8.58% through 2008. Worldwide biotechnology revenues are expected to grow at a compound annual growth rate of 25.96% through 2008 – this large growth rate is not surprising as many biotechnology and biopharmaceutical companies are just now moving products ...
The MICROLAB® NIMBUS is Hamilton Company's newest automated multi-channel pipetting platform, offering a high density deck layout in a body small enough ...
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