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Pharmaceuticals
Research Library
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Capsugel
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Aptalis Pharmaceutical Technologies
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Orally disintegrating tablets (ODTs) are unique dosage forms that facilitate improved patient convenience and compliance. However, they also come with unique formulation and manufacturing chalenges, requiring specialised expertise, in order to create a product that appeals to customers while improving on disintegration and dissolution rates. Aptalis employs a proprietary external lubrication ...
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ValueCentric
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Cephalon, Inc. is among the world’s fastest-growing biopharmaceutical companies. With approximately 3,000 employees worldwide, Cephalon specializes in drugs that treat and manage neurological diseases, sleep disorders, cancer and pain. The company is headquartered in Frazer, PA, and markets more than 20 products internationally, with four proprietary products in the United States.
Following the ...
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SOTAX Corp.
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Excerpted from Pharmaceutical Formulation & Quality magazine, November 2004
USP4 Apparatus Fosters Dissolution Determination
The flow through cell can be used to determine the apparent rate of dissolution without any modification of the drug
cal properties of different batches of phar- macopoeial drug substances by performing a dissolution test with the flow through apparatus.
Materials, ...
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EMD Millipore Bioscience
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Cyclooxygenases (COXs), also known as prostaglandin H synthases, are fatty acid oxygenases that contain about 600 amino acid residues and act on arachidonic acid to generate prostaglandins (PG). All vertebrates contain two COX genes: one encoding the constitutive COX-1 and another inducible COX-2. COX-1 and COX-2 share approximately 60-65% amino acid identity. These COX isoforms are bifunctional ...
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