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p53 and MDM2: Partners in Repair and Death
EMD Millipore Bioscience
In unstressed cells, p53 is latent and is maintained at low levels by targeted degradation mediated by MDM2. Through its binding to p53, MDM2 can shuttle p53 out of the nucleus into the cytoplasm for degradation. When normal mammalian cells are subjected to stress signals, such as hypoxia, radiation, and chemotherapeutic drugs, p53 is phosphorylated at multiple sites, including those involved in ...
 
NuAire | Cross contamination in a Biological Safety Cabinet
NuAire Inc.
Impact of Class II Biological Safety Cabinet Downflow Velocity on Cross Contamination Over the last several years, Biological Safety Cabinet (BSC) manufacturers have lowered downflow velocity while maintaining inflow velocity in an effort to increase energy efficiency, reduce exhaust system requirements and lower BSC Noise and vibration levels. However, the lowering of downflow velocity may come ...
 
Regulatory Overview of Antimicrobial Products Bearing Public Health Claims
ATS Labs
Antimicrobial products intended to protect the public health are regulated as pesticides in the United States by the Environmental Protection Agency (EPA). Before manufacturers can sell pesticides in the United States, EPA must evaluate the pesticides thoroughly to ensure that they meet federal safety standards to protect human health and the environment. This white paper, featuring a convenient ...
 
United States Biological ELISA General Protocol
United States Biological
The protocols described in this paper are for general application. Any product specific protocol supercedes these general recommendations: •Direct ELISA is suitable for the detection of protein-based antigens can be performed when the desired antibody is available in a conjugated form. •Indirect ELISA is required if the primary antibody is not conjugated. With Indirect ELISA, a conjugated ...
 
A Clinical Perspective on IV Medication Delivery
Baxter's BioPharma Solutions business
A Clinical Perspective on IV Medication Delivery Exploring the Benefits of Ready-to-Use IV Products A Clinical Perspective on IV Medication Delivery Management of medication delivery through intravenous (IV) administration is a complex and challenging task for pharmacists. Many considerations influence IV administration including patient safety, medical efficacy, budget implications and labor ...
 
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The Jackson Laboratory Pharmaceuticals

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Jackson Laboratory's legacy of genetic discovery The Jackson Laboratory The Jackson Laboratory has been a significant force in genetic discovery for more than 80 years. We discover the genetic basis for preventing, treating ...
 
NuAire CellGard Biological Safety Cabinets Offers More Under the Hood NuAire Inc.
 

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