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Pharmaceuticals
Research Library
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EMD Chemicals Inc.
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Telomerase is a specialized ribonucleoprotein composed of telomerase reverse transcriptase (TERT), an intrinsic RNA template (TR), and several associated proteins. Its main function is to stabilize telomeres, which protect chromosomes from recombination and end-to-end fusion.
Telomeres also recognize DNA damage and control the replicative capability of cells. With each cell division some of ...
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Thermo Scientific Cell Culture and Bioprocessing
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X-ray microanalysis on the scanning electron microscope (SEM) is accomplished using either Energy Dispersive Spectrometry (EDS) or Wavelength Dispersive Spectroscopy (WDS).
EDS developed in the early 1970 is a flexible elemental analysis method used for qualitative and quantitative composition determinations of solid, liquid, thin film and powder samples. The overlap of analyte peaks in complex ...
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Rules-Based Medicine
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Accurate measurement of immune activity in relation to therapeutic dosing is an important part of many clinical trials, yet is poorly addressed by traditional techniques. Typical immune activity monitoring is performed using isolated leukocytes or even sorted sub- population culturing methods followed by an analytical measurement. These methods require the shipment of intact blood samples to a ...
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Parameter Generation & Control, Inc.
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On the surface, providing a specified humidity and temperature for stability testing may appear easier to achieve than the 5% RH and 2C ICH guidelines would seem to indicate. The ability to control humidity at 2% does not mean that you are safely within the 5% RH tolerance dictated by ICH.
The ability to produce a recording, display, or printout that is within a specified tolerance may not be a ...
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Cetero Research
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A crucial element in the development of topical and transdermal drug products is evaluation of the percutaneous absorption of the active pharmaceutical ingredient (API). Generally, the goal for topical products is to maximize cutaneous delivery of the API, whereas for transdermal products the goal is to achieve a specific rate of absorption sufficient to achieve a systemic blood level within the ...
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